3,3′,5-Triiodothyroacetic acid
3,3′,5-Triiodothyroacetic acid (CAS: 51-24-1) is a potent thyromimetic compound with the molecular formula C14H9I3O4. It is structurally related to thyroid hormones and is primarily employed in biochemical research. This substance is recognized for its role in studying thyroid hormone receptor interactions and metabolic regulation. It serves as a valuable tool in understanding endocrine pathways and cellular responses related to thyroid function.
- IUPAC
- 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylacetic acid
- Synonyms
- 51-24-1C14H9I3O44-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylacetic acid

Biochemical Research
Used as a thyromimetic agent in studies investigating thyroid hormone receptor alpha and beta (THRA, THRB) pathways in human and rat models. It aids in understanding gene regulation and metabolic processes controlled by thyroid hormones.
Cell Biology Studies
Employed to probe cellular mechanisms influenced by thyroid hormone activity. Its application helps researchers elucidate complex signalling cascades and their impact on cell function and differentiation.
Organic Synthesis
Serves as a building block or intermediate in the synthesis of more complex organic molecules. Its unique structure, featuring multiple iodine substituents, makes it a useful starting material in specialized chemical synthesis.
| Molecular weight | 621.93 |
|---|---|
| Empirical formula | C14H9I3O4 |
| Assay | ≥90% |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... THRA(7067), THRB(7068)rat ... Thra(81812), Thrb(24831) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3′,5-Triiodothyroacetic acid used for?
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3,3′,5-Triiodothyroacetic acid is primarily used in biochemical research as a thyromimetic agent to study thyroid hormone receptor interactions and metabolic regulation. It is also utilized in cell biology and as a building block in organic synthesis.
What is the CAS number and formula for 3,3′,5-Triiodothyroacetic acid?
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The CAS number is 51-24-1 and the empirical formula is C14H9I3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3′,5-Triiodothyroacetic acid with an assay of ≥90%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,3′,5-Triiodothyroacetic acid be handled and stored?
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3,3′,5-Triiodothyroacetic acid is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It should be handled with appropriate personal protective equipment (P280) in a well-ventilated area. Store at -20°C.
Is 3,3′,5-Triiodothyroacetic acid a controlled substance?
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The provided data does not indicate that 3,3′,5-Triiodothyroacetic acid is a controlled substance.
How is this chemical packed, shipped, and exported by TSS?
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Tech Serve Solutions packs, ships, and exports chemicals according to international regulations, ensuring safe and secure transit. Specific packaging details depend on quantity and destination.
How can I request a sample or quote for 3,3′,5-Triiodothyroacetic acid?
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To request a sample or quote, please contact our sales department through the website or by phone, providing the product name and CAS number.
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