6-Chloro-8-fluoroquinoline
6-Chloro-8-fluoroquinoline (CAS: 52200-53-0) is a heterocyclic organic compound with the molecular formula C9H5ClFN and a molecular weight of 181.59 g/mol. It serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its fluorinated quinoline structure makes it an important intermediate for the development of novel therapeutic agents and functional materials. TSS supplies this compound with an assay of 95%.
- IUPAC
- 8-Fluoro-6-chloroquinoline
- Synonyms
- 8-Fluoro-6-chloroquinoline

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs), leveraging its fluorinated quinoline scaffold for drug discovery and development.
Agrochemical Synthesis
Serves as a key intermediate in the creation of novel pesticides, herbicides, and fungicides, contributing to advancements in crop protection.
Material Science
Incorporated into the development of advanced materials due to its unique heterocyclic and fluorinated structure, potentially for electronic or optical applications.
Research and Development
A versatile building block employed in academic and industrial research laboratories for exploring new chemical transformations and synthesizing complex molecules.
| Molecular weight | 181.59 |
|---|---|
| Empirical formula | C9H5ClFN |
| Assay | 95% |
| Melting point | 76-81 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloro-8-fluoroquinoline used for?
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6-Chloro-8-fluoroquinoline is primarily used as a building block in organic synthesis, with significant applications as an intermediate in the pharmaceutical and agrochemical industries. It is also utilised in material science and general chemical research and development.
What are the CAS number and formula for 6-Chloro-8-fluoroquinoline?
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The CAS number for 6-Chloro-8-fluoroquinoline is 52200-53-0, and its empirical formula is C9H5ClFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloro-8-fluoroquinoline with a purity of 95% (assay). This compound is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling 6-Chloro-8-fluoroquinoline?
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6-Chloro-8-fluoroquinoline is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, should be used. Handle in a well-ventilated area.
How is 6-Chloro-8-fluoroquinoline packed and shipped?
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6-Chloro-8-fluoroquinoline is carefully packed in accordance with international shipping regulations for hazardous materials. TSS ensures secure packaging for global export.
How can I request a sample or quote for 6-Chloro-8-fluoroquinoline?
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To request a sample or a quote for 6-Chloro-8-fluoroquinoline, please contact our sales team through the website or by calling our direct line.
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