3,3′,5-Triiodo-L-thyronine
3,3′,5-Triiodo-L-thyronine (CAS 6893-02-3) is a triiodinated thyroid hormone derivative with the molecular formula C15H12I3NO4 and a molecular weight of 650.97 g/mol. It is primarily employed in chemical biology research for investigating thyroid hormone pathways and as a reagent in chemical synthesis. Its specific stereochemistry and high purity make it valuable for detailed biochemical studies.
- IUPAC
- O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Liothyronine,T3
- Synonyms
- 6893-02-3C15H12I3NO4O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosineLiothyronineT3

Chemical Biology Research
Utilised in studies focusing on thyroid hormone receptor binding and signalling mechanisms. Its defined structure allows for precise investigation of biological pathways.
Chemical Synthesis
Serves as a specialised building block or reference compound in the synthesis of complex organic molecules and potential pharmaceutical agents.
Biochemical Assays
Employed as a standard or control in various biochemical and enzymatic assays related to thyroid hormone metabolism and function.
| Molecular weight | 650.97 |
|---|---|
| Empirical formula | C15H12I3NO4 |
| Assay | 95% |
| Optical activity | [α]20/D +23.0°, c = 2 in ethanol or 0.1 N HCl |
| Storage temperature | −20°C |
| Melting point | 234-238 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3′,5-Triiodo-L-thyronine used for?
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3,3′,5-Triiodo-L-thyronine (CAS 6893-02-3) is primarily used in chemical biology research for studying thyroid hormone pathways and as a reagent in chemical synthesis. It also finds application in biochemical assays.
What is the CAS number and molecular formula for 3,3′,5-Triiodo-L-thyronine?
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The CAS number for 3,3′,5-Triiodo-L-thyronine is 6893-02-3, and its molecular formula is C15H12I3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3′,5-Triiodo-L-thyronine with an assay of 95%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any pharmacopoeial grade.
How should 3,3′,5-Triiodo-L-thyronine be handled safely?
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Handle 3,3′,5-Triiodo-L-thyronine with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation).
Is 3,3′,5-Triiodo-L-thyronine a controlled substance?
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The provided data does not indicate that 3,3′,5-Triiodo-L-thyronine is a controlled substance.
How is 3,3′,5-Triiodo-L-thyronine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is typically stored at -20°C and will be packaged and shipped according to international regulations for chemical exports.
How can I request a sample or quote for 3,3′,5-Triiodo-L-thyronine?
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To request a sample or a quote for 3,3′,5-Triiodo-L-thyronine, please contact our sales department through the TSS website or by calling our customer service line.
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