3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-PROXYL
3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-PROXYL (CAS 68407-07-8), with the molecular formula C17H27N3O5 and a molecular weight of 353.41 g/mol, is a stable nitroxide radical. This PROXYL derivative is characterised by its maleimide functional group, making it suitable for conjugation to thiol-containing biomolecules. It serves as a valuable building block in chemical synthesis, particularly for creating spin-labelled compounds for biophysical studies.
- IUPAC
- 3-([(2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethyl)amino]carbonyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy,3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical
![3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-PROXYL (C17H27N3O5) — chemical structure, CAS 68407-07-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F68407-07-8.png&w=3840&q=75)
Bioconjugation Reagent
The maleimide moiety allows for selective covalent attachment to thiol groups present in peptides, proteins, and other biomolecules. This enables the introduction of the stable PROXYL radical for applications in electron paramagnetic resonance (EPR) spectroscopy.
Spin Labeling
As a stable free radical, it functions as a spin label. When attached to a molecule of interest, its EPR signal provides information about the local environment, dynamics, and structure of the labelled entity.
Materials Science
The compound can be incorporated into polymers or materials to impart specific magnetic or redox properties. Its spin-labelled nature can be leveraged for developing advanced functional materials.
Research Chemical
It is widely employed in academic and industrial research settings for investigating reaction mechanisms, studying molecular interactions, and developing novel chemical probes.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C17H27N3O5 |
| Melting point | 95-98 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-PROXYL used for?
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3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-PROXLY is used as a spin label and a bioconjugation reagent. It allows for the introduction of a stable nitroxide radical onto thiol-containing biomolecules for studies using EPR spectroscopy, and also finds application in materials science and general chemical synthesis.
What are the CAS number and molecular formula for this compound?
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The CAS number is 68407-07-8 and the molecular formula is C17H27N3O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and development use. The specific grade and purity are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety precautions for handling 3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-PROXYL?
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This compound is classified as a Warning with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is this chemical packed and shipped?
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Tech Serve Solutions exports chemicals globally, ensuring compliance with all relevant shipping regulations. Packaging is designed to maintain product integrity and safety during transit. Please contact us for specific shipping and export details.
How can I request a sample or quote?
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To request a sample or a quotation, please visit the 'Contact Us' section of our website or call our sales department. Provide the product name and CAS number for a prompt response.
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