3-[(Trimethylsilyl)ethynyl]thiophene
3-[(Trimethylsilyl)ethynyl]thiophene (CAS: 130995-13-0; Formula: C9H12SSi; MW: 180.34) is a versatile organosilicon compound incorporating a thiophene ring and a trimethylsilyl-protected ethynyl group. It serves as a valuable building block in organic synthesis, particularly for constructing complex molecules in materials science and medicinal chemistry research. Its unique structure allows for selective functionalization and incorporation into various chemical architectures.
![3-[(Trimethylsilyl)ethynyl]thiophene (C9H12SSi) — chemical structure, CAS 130995-13-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F130995-13-0.png&w=3840&q=75)
Organic Synthesis Building Block
Utilised as a key intermediate in the synthesis of novel organic compounds. The trimethylsilyl group provides protection and can be readily removed to reveal the terminal alkyne for further reactions.
Materials Science Research
Incorporated into the design and synthesis of advanced materials, potentially for electronic or optical applications, leveraging the properties of the thiophene moiety.
Medicinal Chemistry
Serves as a scaffold or intermediate in the development of new pharmaceutical candidates, where the thiophene ring is a common pharmacophore.
| Molecular weight | 180.34 |
|---|---|
| Empirical formula | C9H12SSi |
| Assay | 97% |
| Melting point | 36-41 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-[(Trimethylsilyl)ethynyl]thiophene primarily used for?
+
3-[(Trimethylsilyl)ethynyl]thiophene is primarily used as a building block in organic synthesis, particularly in materials science and medicinal chemistry research for the construction of complex organic molecules.
What is the CAS number and chemical formula for 3-[(Trimethylsilyl)ethynyl]thiophene?
+
The CAS number is 130995-13-0 and the chemical formula is C9H12SSi.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent it as meeting USP, BP, EP, or any pharmacopoeia standards.
How should 3-[(Trimethylsilyl)ethynyl]thiophene be handled safely?
+
This compound is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation or respiratory protection.
Is 3-[(Trimethylsilyl)ethynyl]thiophene a controlled substance?
+
The provided data does not indicate that 3-[(Trimethylsilyl)ethynyl]thiophene is a controlled substance.
How is this chemical exported or shipped?
+
This chemical is shipped according to relevant transportation regulations, with a classification of NA 1993 / PGIII.
How can I request a sample or quote?
+
Please contact our sales department via the website or direct email to request a sample or a quotation for 3-[(Trimethylsilyl)ethynyl]thiophene.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis