Estriol
Estriol (CAS: 50-27-1), a C18H24O3 steroid, is a naturally occurring estrogen. With a molecular weight of 288.38 g/mol, it plays a role in various biological processes. Estriol is utilised in chemical synthesis, particularly in asymmetric synthesis and as a chiral building block for complex molecules. It is also a subject of study in cell biology and nutrition research, contributing to our understanding of phytochemicals.
- IUPAC
- 1,3,5(10)-Estratriene-3,16α,17β-triol,16α-Hydroxyestradiol,3,16α,17β-Trihydroxy-1,3,5(10)-estratriene
- Synonyms
- 1,3,5(10)-Estratriene-3,16α,17β-triol16α-Hydroxyestradiol3,16α,17β-Trihydroxy-1,3,5(10)-estratriene

Chemical Synthesis
Estriol serves as a valuable precursor and chiral building block in the synthesis of complex organic molecules. Its defined stereochemistry is essential for asymmetric synthesis pathways.
Cell Biology Research
Used in studies investigating cellular mechanisms and responses related to steroid hormones and their interactions within biological systems.
Nutrition Research
Applied in nutritional science to explore the biochemical pathways and physiological effects of natural compounds.
Phytochemical Analysis
Estriol is categorised under phytochemicals, enabling its use in research focusing on plant-derived compounds and their biological activities.
| Molecular weight | 288.38 |
|---|---|
| Empirical formula | C18H24O3 |
| Assay | ≥97.0% (HPLC) |
| Grade | purum |
| Optical activity | [α]20/D +57±2°, c = 0.4% in dioxane |
| Loss on drying | ≤0.5% loss on drying, 110 °C |
| Melting point | 280-282 °C(lit.)280-282 °C |

Hazard statements
- H351Suspected of causing cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 60-61-40 |
| Safety statements (S) | 53-36/37-45 |
| Ignition residue | ≤0.1% (as SO4) |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Estriol used for?
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Estriol is utilised in chemical synthesis, particularly in asymmetric synthesis and as a chiral building block for complex molecules. It is also a subject of study in cell biology and nutrition research, contributing to our understanding of phytochemicals.
What is the CAS number and formula for Estriol?
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The CAS number for Estriol is 50-27-1, and its chemical formula is C18H24O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Estriol with a purity of ≥97.0% (HPLC) and a grade of purum. We do not represent this product as USP, BP, or EP grade.
How should Estriol be handled safely?
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Estriol is classified as a dangerous substance. Handle with appropriate personal protective equipment, including eyeshields and chemical-resistant gloves. Ensure adequate ventilation and use a suitable respirator if airborne exposure is possible. Avoid exposure and seek medical attention if necessary, referring to the H351 and H360 hazard statements.
How is Estriol packed, shipped, and exported?
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Estriol is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for Estriol?
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To request a sample or a quotation for Estriol, please contact our sales team through the website or by phone, providing your specific requirements.
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