1,1,1-Trifluoro-2-propanol
1,1,1-Trifluoro-2-propanol (CAS: 374-01-6), with the linear formula CF3CH(OH)CH3 and a molecular weight of 114.07 g/mol, is a fluorinated alcohol. It serves as a valuable building block in organic synthesis and chemical research. Its unique trifluoromethyl group imparts specific properties, making it useful in the development of novel compounds and materials across various scientific disciplines.
- Synonyms
- 374-01-6CF3CH(OH)CH3

Organic Synthesis Reagent
This trifluorinated alcohol is employed as a versatile reagent in organic synthesis. It can be used to introduce the trifluoromethyl moiety or participate in reactions characteristic of secondary alcohols, facilitating the creation of complex molecules.
Building Block for Fluorinated Compounds
As an organic building block, 1,1,1-Trifluoro-2-propanol is instrumental in synthesizing more complex fluorinated organic compounds. These compounds often exhibit unique chemical and physical properties relevant to pharmaceuticals and materials science.
Research and Development
In research and development settings, this chemical is utilised for exploring new reaction pathways and developing novel chemical entities. Its distinct structure makes it a subject of interest in academic and industrial research laboratories.
| Molecular weight | 114.07 |
|---|---|
| Linear formula | CF3CH(OH)CH3 |
| Assay | 97% |
| Boiling point | 81-82 °C(lit.) |
| Density | 1.259 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.316(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 18 °C / 64.4 °F |
| Transport (UN / ADR) | UN 1987BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1,1-Trifluoro-2-propanol used for?
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1,1,1-Trifluoro-2-propanol is primarily used as a building block in organic synthesis and for the development of novel fluorinated compounds in research and development.
What is the CAS number and formula for 1,1,1-Trifluoro-2-propanol?
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The CAS number is 374-01-6 and the linear formula is CF3CH(OH)CH3.
What grade and purity does Tech Serve Solutions supply for 1,1,1-Trifluoro-2-propanol?
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Tech Serve Solutions supplies 1,1,1-Trifluoro-2-propanol with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 1,1,1-Trifluoro-2-propanol be handled safely?
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1,1,1-Trifluoro-2-propanol is a flammable liquid and vapour (H225) and causes skin irritation (H315) and respiratory irritation (H335). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, and suitable gloves, along with adequate ventilation. Always refer to the Safety Data Sheet before use.
Is 1,1,1-Trifluoro-2-propanol shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,1,1-Trifluoro-2-propanol, and handles international shipments.
How can I request a sample or quote for 1,1,1-Trifluoro-2-propanol?
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To request a sample or a quote for 1,1,1-Trifluoro-2-propanol, please contact our sales team through the TSS website or direct inquiry channels.
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