1,1,1-Trifluoro-3-phenyl-2-propanone
1,1,1-Trifluoro-3-phenyl-2-propanone (CAS 350-92-5) is a trifluoromethyl ketone with the linear formula C6H5CH2COCF3 and a molecular weight of 188.15 g/mol. It serves as a valuable building block in organic synthesis. This compound is typically employed in the chemical industry for the development of novel molecules and intermediates, leveraging its unique trifluoromethyl ketone functionality.
- Synonyms
- 350-92-5C6H5CH2COCF3

Organic Synthesis Intermediate
Utilised as a versatile building block in the synthesis of more complex organic molecules. Its trifluoromethyl ketone moiety offers unique reactivity for various chemical transformations.
Pharmaceutical Research
Employed in the development of novel pharmaceutical candidates. The incorporation of trifluoromethyl groups can influence the pharmacokinetic and metabolic properties of drug molecules.
Material Science Applications
Investigated for potential use in the creation of new materials. The presence of fluorine atoms can impart specific properties such as thermal stability and altered surface characteristics.
| Molecular weight | 188.15 |
|---|---|
| Linear formula | C6H5CH2COCF3 |
| Assay | 96% |
| Boiling point | 51-52 °C/2 mmHg(lit.) |
| Density | 1.22 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.444(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1224C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1,1-Trifluoro-3-phenyl-2-propanone used for?
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1,1,1-Trifluoro-3-phenyl-2-propanone is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates and potentially in material science.
What are the CAS number and chemical formula for this compound?
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The CAS number is 350-92-5, and the linear chemical formula is C6H5CH2COCF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,1,1-Trifluoro-3-phenyl-2-propanone with a minimum assay of 96%. This is suitable for research and general chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How is 1,1,1-Trifluoro-3-phenyl-2-propanone handled and stored?
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This compound is a flammable liquid and vapour (H226). It should be kept away from heat, hot surfaces, sparks, open flames, and other ignition sources. Use only non-sparking tools and take precautionary measures against static discharge. Appropriate personal protective equipment, including eyeshields and chemical-resistant gloves, should be worn. Store in a well-ventilated place.
Is 1,1,1-Trifluoro-3-phenyl-2-propanone a controlled substance?
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The provided safety data does not indicate that 1,1,1-Trifluoro-3-phenyl-2-propanone is a controlled substance.
How can I request a quote or sample for 1,1,1-Trifluoro-3-phenyl-2-propanone?
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To request a quote or sample, please contact our sales team through the website or by phone, specifying the product name (1,1,1-Trifluoro-3-phenyl-2-propanone) and CAS number (350-92-5).
How is this chemical shipped internationally?
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1,1,1-Trifluoro-3-phenyl-2-propanone is shipped internationally as a UN 1224C 3 / PGIII classified flammable liquid, adhering to all relevant transportation regulations.
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