2-(Trimethylsilyl)thiazole
2-(Trimethylsilyl)thiazole (CAS 79265-30-8), with the empirical formula C6H11NSSi and a molecular weight of 157.31 g/mol, is a valuable heterocyclic building block. This organosilicon compound serves as a versatile reagent in organic synthesis, particularly for introducing the thiazole moiety into more complex molecular architectures. It is frequently employed in the development of novel chemical entities and is a key intermediate in various chemical research applications.
- IUPAC
- 2-Thiazolyltrimethylsilane,2-TST
- Synonyms
- 2-Thiazolyltrimethylsilane

Organic Synthesis Reagent
Utilised as a building block in the synthesis of complex organic molecules, particularly those containing a thiazole ring. Its trimethylsilyl group facilitates specific chemical transformations and coupling reactions.
Pharmaceutical Intermediate
Serves as a precursor or intermediate in the development of pharmacologically active compounds. The thiazole core is present in numerous drugs, making this reagent critical for drug discovery research.
Chemical Research and Development
Employed in academic and industrial R&D settings for exploring new synthetic pathways and creating novel chemical structures. Its unique reactivity profile makes it a subject of interest in mechanistic studies.
| Molecular weight | 157.31 |
|---|---|
| Empirical formula | C6H11NSSi |
| Assay | 96% |
| Boiling point | 56-57 °C/10 mmHg(lit.) |
| Density | 0.985 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.497(lit.) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trimethylsilyl)thiazole primarily used for?
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2-(Trimethylsilyl)thiazole is primarily used as a building block in organic synthesis, particularly for incorporating the thiazole ring into complex molecules, and as an intermediate in pharmaceutical research and development.
What is the CAS number and empirical formula for 2-(Trimethylsilyl)thiazole?
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The CAS number is 79265-30-8 and the empirical formula is C6H11NSSi.
What grade and purity does Tech Serve Solutions supply for 2-(Trimethylsilyl)thiazole?
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Tech Serve Solutions supplies 2-(Trimethylsilyl)thiazole with an assay of 96%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 2-(Trimethylsilyl)thiazole be handled safely?
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2-(Trimethylsilyl)thiazole is a warning substance that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation.
How is 2-(Trimethylsilyl)thiazole shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. 2-(Trimethylsilyl)thiazole is shipped and exported in compliance with all relevant regulations for hazardous materials, under NA 1993 / PGIII classification.
How can I request a sample or quote for 2-(Trimethylsilyl)thiazole?
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To request a sample or a quote for 2-(Trimethylsilyl)thiazole, please contact our sales team through the website or by phone, providing your specific requirements.
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