2-(Trimethylsilyl)ethanethiol
2-(Trimethylsilyl)ethanethiol (CAS: 18143-30-1) is a sulfur-containing organosilicon compound with the linear formula (CH3)3SiCH2CH2SH and a molecular weight of 134.32 g/mol. It serves as a valuable building block in organic synthesis, particularly in reactions involving sulfur functionalities. This compound is primarily utilised in research and development settings for creating more complex molecules within chemical synthesis pathways.
- IUPAC
- (2-Mercaptoethyl)trimethylsilane,BEST
- Synonyms
- (2-Mercaptoethyl)trimethylsilane

Organic Synthesis Intermediate
2-(Trimethylsilyl)ethanethiol functions as a versatile building block in organic synthesis. Its thiol group allows for various coupling and derivatisation reactions, enabling the construction of diverse molecular architectures.
Research and Development
This compound is employed in laboratory settings for exploring novel chemical transformations and developing new synthetic methodologies. Its specific structure makes it useful for introducing protected thiol groups or for silane-based coupling reactions.
Material Science Applications
The presence of both a thiol and a silyl group suggests potential applications in material science, such as surface modification or the development of functionalised polymers, although specific uses are research-dependent.
| Molecular weight | 134.32 |
|---|---|
| Linear formula | (CH3)3SiCH2CH2SH |
| Assay | 95% |
| Boiling point | 144-146 °C(lit.)62-63 °C/43 mmHg(lit.) |
| Density | 0.839 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.454(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 49 °C / 120.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trimethylsilyl)ethanethiol used for?
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2-(Trimethylsilyl)ethanethiol is primarily used as a building block in organic synthesis and for research and development purposes, enabling the creation of complex molecules and exploring new synthetic routes.
What is the CAS number and formula for 2-(Trimethylsilyl)ethanethiol?
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The CAS number is 18143-30-1, and its linear formula is (CH3)3SiCH2CH2SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trimethylsilyl)ethanethiol with an assay of 95%. It is suitable for research and chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should 2-(Trimethylsilyl)ethanethiol be handled safely?
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2-(Trimethylsilyl)ethanethiol is a flammable liquid and vapour (H226) and can cause skin (H315), eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including safety glasses, gloves, and respiratory protection, in a well-ventilated area, and keep away from heat and ignition sources.
How is 2-(Trimethylsilyl)ethanethiol packed, shipped, and exported?
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2-(Trimethylsilyl)ethanethiol is packed according to industry standards for flammable liquids and exported globally by Tech Serve Solutions, adhering to all relevant transportation regulations.
How can I request a quote or sample for 2-(Trimethylsilyl)ethanethiol?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our website or by phone, providing your contact details and the product CAS number 18143-30-1.
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