2-(Trimethylsilyl)ethanesulfonamide
2-(Trimethylsilyl)ethanesulfonamide (CAS: 125486-96-6) is a key organic building block with the linear formula (CH3)3SiCH2CH2SO2NH2 and a molecular weight of 181.33 g/mol. This compound serves as a useful reagent for introducing a protected nitrogen functionality via the SES group, which can be selectively cleaved using fluoride ion. It is primarily utilised in chemical synthesis and organic building block applications.
- IUPAC
- SES-NH2
Nitrogen Protection
This compound is valuable for introducing a nitrogen atom protected with the 2-(Trimethylsilyl)ethanesulfonyl (SES) group. This protection strategy allows for selective deprotection under specific reaction conditions.
Fluoride-Mediated Deprotection
The SES protecting group can be efficiently removed using fluoride ion sources, making 2-(Trimethylsilyl)ethanesulfonamide a convenient reagent in synthetic routes requiring selective nitrogen deprotection.
Organic Synthesis Intermediate
As an organic building block, it facilitates complex molecule construction in research and development laboratories, contributing to the synthesis of novel compounds.
| Molecular weight | 181.33 |
|---|---|
| Linear formula | (CH3)3SiCH2CH2SO2NH2 |
| Assay | 90% |
| Application | Useful reagent for introduction of a SES-protected nitrogen functionality, which can be cleaved with fluoride ion.1 |
| Melting point | 81-87 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trimethylsilyl)ethanesulfonamide used for?
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2-(Trimethylsilyl)ethanesulfonamide is used as a reagent for introducing a SES-protected nitrogen functionality, which can be cleaved with fluoride ion, and serves as an organic building block in chemical synthesis.
What is the CAS number and formula for 2-(Trimethylsilyl)ethanesulfonamide?
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The CAS number is 125486-96-6 and the linear formula is (CH3)3SiCH2CH2SO2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trimethylsilyl)ethanesulfonamide with an assay of 90%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
What are the safety precautions for handling 2-(Trimethylsilyl)ethanesulfonamide?
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This compound is classified as a GHS07 warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid breathing dust.
How is 2-(Trimethylsilyl)ethanesulfonamide shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trimethylsilyl)ethanesulfonamide, adhering to all necessary regulations for international shipment.
How can I request a quote or sample for 2-(Trimethylsilyl)ethanesulfonamide?
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Please contact our sales team via the website or directly to request a quote or a sample of 2-(Trimethylsilyl)ethanesulfonamide.
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