2-(Methanesulfonylamino)phenylboronic acid pinacol ester
2-(Methanesulfonylamino)phenylboronic acid pinacol ester (CAS 380430-60-4) is an organoboron compound with the molecular formula C13H20BNO4S and a molecular weight of 297.18 g/mol. It serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. Its utility lies in the introduction of the N-(2-boronophenyl)methanesulfonamide moiety into complex molecules, finding applications in pharmaceutical research and materials science.
- IUPAC
- N-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide
Suzuki-Miyaura Cross-Coupling Reactions
This pinacol boronate ester is widely used as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of new carbon-carbon bonds by reacting with aryl or vinyl halides and pseudohalides.
Medicinal Chemistry
The compound is employed in the synthesis of novel drug candidates and pharmaceutical intermediates. The phenylboronic acid ester moiety can be readily functionalized to create diverse molecular scaffolds of biological interest.
Materials Science
It can be incorporated into the synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or conductive polymers, where precise molecular architecture is crucial for desired electronic or optical properties.
Organic Synthesis Reagent
As a versatile organometallic reagent, it enables the efficient construction of complex organic molecules, serving as a key intermediate in multi-step synthetic pathways.
| Molecular weight | 297.18 |
|---|---|
| Empirical formula | C13H20BNO4S |
| Assay | 97% |
| Melting point | 130-134 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Methanesulfonylamino)phenylboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. It finds applications in medicinal chemistry for drug discovery and in materials science.
What is the CAS number and molecular formula?
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The CAS number for 2-(Methanesulfonylamino)phenylboronic acid pinacol ester is 380430-60-4, and its molecular formula is C13H20BNO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Methanesulfonylamino)phenylboronic acid pinacol ester with an assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should this chemical be handled?
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This compound is classified as harmful if swallowed (H302). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Avoid dust formation and inhalation.
How is this product packed and shipped?
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As a specialist global supplier, Tech Serve Solutions ensures appropriate packing for safe transport. We export chemicals worldwide, adhering to international shipping regulations.
How can I request a sample or quote?
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To request a sample or obtain a quotation for 2-(Methanesulfonylamino)phenylboronic acid pinacol ester, please contact our sales department via the website or direct inquiry.
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