2-(Methanesulfonyl)ethyl succinimidyl carbonate
2-(Methanesulfonyl)ethyl succinimidyl carbonate (CAS: 57903-15-8, Formula: C8H11NO7S) is a specialized chemical reagent with a molecular weight of 265.24. It is primarily utilized in organic synthesis and chemical biology for amine protection. This compound serves as a valuable tool in peptide chemistry and the development of protecting and derivatizing reagents, contributing to advancements in synthetic chemistry.
- IUPAC
- N-[2-(Methylsulfonyl)ethoxycarbonyloxy]succinimide,MSC-ONSu

Amine Protection
This compound is employed as a protecting group for amines in multi-step organic syntheses. Its succinimidyl carbonate moiety allows for controlled introduction and removal under specific reaction conditions.
Peptide Chemistry
In peptide synthesis, it can be used to selectively protect amino groups on amino acids or peptide fragments. This ensures regioselective coupling reactions and prevents unwanted side reactions during chain elongation.
Chemical Biology Research
Researchers utilize this reagent in chemical biology to modify biomolecules containing amine functionalities. This enables the study of protein structure, function, and interactions.
Synthetic Reagent
As a versatile synthetic reagent, it facilitates the preparation of complex organic molecules and intermediates. Its specific reactivity profile makes it useful in various derivatization strategies.
| Molecular weight | 265.24 |
|---|---|
| Empirical formula | C8H11NO7S |
| Assay | 98% |
| Melting point | 115-118 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Methanesulfonyl)ethyl succinimidyl carbonate used for?
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2-(Methanesulfonyl)ethyl succinimidyl carbonate (CAS: 57903-15-8) is primarily used for amine protection in organic synthesis, peptide chemistry, and chemical biology research. It acts as a protecting and derivatizing reagent.
What is the CAS number and formula for this compound?
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The CAS number is 57903-15-8, and the empirical formula is C8H11NO7S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Methanesulfonyl)ethyl succinimidyl carbonate with an assay of 98%. It is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 2-(Methanesulfonyl)ethyl succinimidyl carbonate be handled?
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This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Can I request a sample or quote?
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Yes, you can request a sample or a quote for 2-(Methanesulfonyl)ethyl succinimidyl carbonate directly through our website or by contacting our sales team.
Is this compound exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Methanesulfonyl)ethyl succinimidyl carbonate.
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