2-Hydroxy-4-(trifluoromethyl)pyrimidine
2-Hydroxy-4-(trifluoromethyl)pyrimidine (CAS: 104048-92-2; Formula: C5H3F3N2O; MW: 164.09) is a fluorinated heterocyclic compound. It serves as a valuable building block in chemical synthesis, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring a pyrimidine core with a trifluoromethyl group, makes it a key intermediate for developing novel biologically active molecules.
- IUPAC
- 4-(Trifluoromethyl)-2(1H)-pyrimidinone,4-(Trifluoromethyl)-2-pyrimidinol
- Synonyms
- 4-(Trifluoromethyl)-2(1H)-pyrimidinone4-(Trifluoromethyl)-2-pyrimidinol
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where the trifluoromethylpyrimidine moiety is incorporated for its potential to modulate drug properties such as metabolic stability and lipophilicity.
Agrochemical Development
Serves as a building block for the creation of new pesticides, herbicides, and fungicides, leveraging the unique electronic and steric properties conferred by the trifluoromethyl group.
Material Science Research
Explored as a component in the development of novel organic materials, dyes, and specialty chemicals due to its distinct structural features.
Organic Synthesis
A versatile reagent for introducing the 4-(trifluoromethyl)pyrimidin-2-ol or related structures into complex organic molecules.
| Molecular weight | 164.09 |
|---|---|
| Empirical formula | C5H3F3N2O |
| Assay | 97% |
| Melting point | 223-227 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxy-4-(trifluoromethyl)pyrimidine used for?
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2-Hydroxy-4-(trifluoromethyl)pyrimidine is primarily used as a building block in chemical synthesis for the development of pharmaceuticals, agrochemicals, and specialty organic materials.
What is the CAS number and molecular formula?
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The CAS number is 104048-92-2 and the molecular formula is C5H3F3N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Hydroxy-4-(trifluoromethyl)pyrimidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Hydroxy-4-(trifluoromethyl)pyrimidine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. It is classified as causing skin irritation, eye irritation, and respiratory irritation (H315, H319, H335).
Is this chemical suitable for use in food or pharmaceuticals?
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This chemical is supplied for research and industrial purposes with a 97% assay. It is not guaranteed to be USP, BP, or EP grade and therefore should not be used in food or medicinal products without further evaluation and processing.
How is 2-Hydroxy-4-(trifluoromethyl)pyrimidine packed and shipped?
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Tech Serve Solutions packs and exports chemicals like 2-Hydroxy-4-(trifluoromethyl)pyrimidine in compliance with international shipping regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample of 2-Hydroxy-4-(trifluoromethyl)pyrimidine, please contact our sales team through the website or by phone.
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