2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile
2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile (CAS 769-28-8), with the molecular formula C8H8N2O and a molecular weight of 148.16 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis, particularly within the realm of pyridine derivatives. This compound is primarily utilised in research and development settings for the creation of more complex molecular structures.
- IUPAC
- 3-Cyano-4,6-dimethyl-2-hydroxypyridine,4,6-Dimethyl-2-hydroxynicotinonitrile
- Synonyms
- 3-Cyano-4,6-dimethyl-2-hydroxypyridine4,6-Dimethyl-2-hydroxynicotinonitrile

Chemical Synthesis
Utilised as a key intermediate in the synthesis of various organic compounds, particularly those involving pyridine rings. Its functional groups allow for diverse chemical transformations.
Heterocyclic Chemistry Research
Serves as a fundamental building block in academic and industrial research focused on developing novel heterocyclic compounds. Its structure lends itself to explorations in medicinal chemistry and material science.
Development of Novel Pyridine Derivatives
A versatile reagent for constructing substituted pyridine systems. Researchers can leverage its structure to design and synthesise new molecules with tailored properties.
| Molecular weight | 148.16 |
|---|---|
| Empirical formula | C8H8N2O |
| Assay | 98% |
| Melting point | 285-287 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile used for?
+
2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile is used as a building block in chemical synthesis and heterocyclic chemistry research, particularly for developing novel pyridine derivatives.
What is the CAS number and formula for 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile?
+
The CAS number is 769-28-8 and the empirical formula (Hill notation) is C8H8N2O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile be handled safely?
+
This compound may cause irritation and is harmful if swallowed, inhaled, or in contact with skin. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust and ensure proper disposal.
Is 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile.
How can I request a sample or quote for 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile?
+
Please contact our sales team via the website or direct telephone to request a sample or obtain a quote for 2-Hydroxy-4,6-dimethylpyridine-3-carbonitrile.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis