2-Fluoro-3-(trifluoromethyl)benzoyl chloride
2-Fluoro-3-(trifluoromethyl)benzoyl chloride (CAS: 208173-19-7) is a fluorinated organic compound with the linear formula C7H3ClF4O and a molecular weight of 226.56 g/mol. It functions as a versatile acylating agent, particularly useful in synthesising complex organic molecules. Its reactive nature makes it a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials where precise fluorination is required.

Organic Synthesis Intermediate
This compound serves as a crucial building block in multi-step organic syntheses. It readily undergoes reactions with nucleophiles, enabling the introduction of the 2-fluoro-3-(trifluoromethyl)benzoyl moiety into target molecules.
Pharmaceutical Research and Development
It is employed in the synthesis of novel pharmaceutical candidates. The presence of fluorine atoms can significantly influence a drug's metabolic stability, lipophilicity, and binding affinity.
Agrochemical Synthesis
2-Fluoro-3-(trifluoromethyl)benzoyl chloride is utilised in the creation of advanced agrochemical compounds, potentially leading to new pesticides or herbicides with enhanced efficacy.
Materials Science
This chemical can be incorporated into the synthesis of specialised polymers or functional materials, leveraging its unique structural features for specific performance characteristics.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 98% |
| Boiling point | 193 °C(lit.) |
| Density | 1.517 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.472(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-(trifluoromethyl)benzoyl chloride used for?
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2-Fluoro-3-(trifluoromethyl)benzoyl chloride is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty materials. It acts as an acylating agent for introducing the 2-fluoro-3-(trifluoromethyl)benzoyl group.
What are the CAS number and molecular formula for 2-Fluoro-3-(trifluoromethyl)benzoyl chloride?
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The CAS number is 208173-19-7 and the linear molecular formula is C7H3ClF4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-(trifluoromethyl)benzoyl chloride with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Fluoro-3-(trifluoromethyl)benzoyl chloride be handled?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with extreme caution, using appropriate personal protective equipment including gloves, goggles, a faceshield, and a suitable respirator. Ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling procedures.
Does Tech Serve Solutions export 2-Fluoro-3-(trifluoromethyl)benzoyl chloride?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-3-(trifluoromethyl)benzoyl chloride, adhering to international shipping regulations (UN 3265, Class 8, PG II).
How can I request a quote or sample for 2-Fluoro-3-(trifluoromethyl)benzoyl chloride?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly, providing your details and the product CAS number (208173-19-7).
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