Sulfaphenazole

CAS 526-08-9C15H14N4O2SBiochemicals & Reagents

Sulfaphenazole (CAS: 526-08-9, C15H14N4O2S) is a chemical compound with a molecular weight of 314.36 g/mol. Primarily recognised for its role as an inhibitor of cytochrome P450 enzymes, it finds significant application in biochemical research. This compound is crucial for studies involving drug and xenobiotic metabolism, as well as for investigating cell signaling pathways. Its specific inhibitory action makes it a valuable tool for researchers in pharmacology and cell biology.

IUPAC: 4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
Synonyms: 4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide

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Sulfaphenazole (C15H14N4O2S) — chemical structure, CAS 526-08-9; Life Science, fine chemical supplied by Tech Serve Solutions

A to CApplication IndexBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCell Signaling EnzymesCytochrome P450 TB enzymesEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymes

01 /Applications

Cytochrome P450 Enzyme Inhibition

Sulfaphenazole is widely used as an inhibitor of specific cytochrome P450 (CYP) enzymes, notably CYP2C18, CYP2C19, and CYP2C9. This property makes it indispensable for in vitro studies aimed at understanding drug metabolism and potential drug-drug interactions.

Drug Metabolism Research

By selectively inhibiting certain CYP isoforms, Sulfaphenazole aids researchers in elucidating the metabolic pathways of various xenobiotics and drugs. This is crucial for drug discovery and development processes.

Cell Signaling Studies

This compound serves as a tool in cell biology to investigate the role of CYP enzymes in cellular signaling pathways. Its application helps in understanding complex biological processes at the cellular level.

Biochemical Research Reagent

As a biochemical reagent, Sulfaphenazole is utilised in various laboratory settings for experimental purposes. Its defined inhibitory activity makes it a reliable choice for specific biochemical assays and analyses.

02 /Properties

Molecular weight	314.36
Empirical formula	C15H14N4O2S
Assay	≥98% (HPLC)
Storage temperature	2-8°C
Melting point	179-183 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

526-08-9

MDL number

MFCD00057226

PubChem substance

24278198

05 /Additional specifications

Gene Information	human ... CYP2C18(1562), CYP2C19(1557), CYP2C9(1559)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Sulfaphenazole used for?

Sulfaphenazole is primarily used as an inhibitor of specific cytochrome P450 enzymes (CYP2C18, CYP2C19, CYP2C9) in biochemical and pharmacological research, particularly for studies on drug metabolism and cell signaling.

What is the CAS number and formula for Sulfaphenazole?

The CAS number for Sulfaphenazole is 526-08-9, and its empirical formula is C15H14N4O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Sulfaphenazole with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should Sulfaphenazole be handled and stored?

Handle Sulfaphenazole with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the compound at 2-8°C.