2-Fluoro-3-(trifluoromethyl)phenol
2-Fluoro-3-(trifluoromethyl)phenol (CAS: 207291-85-8), with the molecular formula C6H3(CF3)OH and a molecular weight of 180.10 g/mol, is a valuable organic building block. This fluorinated phenol is utilised in chemical synthesis for the development of complex molecules. Its unique structure, featuring both a fluorine atom and a trifluoromethyl group, makes it an important intermediate in various research and development applications, particularly within organic chemistry.

Organic Synthesis Intermediate
2-Fluoro-3-(trifluoromethyl)phenol serves as a key intermediate in the synthesis of complex organic molecules. Its fluorinated nature is advantageous for modifying the electronic and lipophilic properties of target compounds in pharmaceutical and agrochemical research.
Fluorinated Building Block
As a fluorinated building block, this compound is employed in the construction of novel fluorinated materials and active pharmaceutical ingredients. The presence of both a hydroxyl and a trifluoromethyl group allows for diverse synthetic transformations.
Research and Development
This chemical is utilised in academic and industrial research laboratories for exploring new synthetic routes and developing innovative chemical entities. Its specific structure offers unique reactivity for advanced chemical studies.
| Molecular weight | 180.10 |
|---|---|
| Linear formula | FC6H3(CF3)OH |
| Assay | 97% |
| Boiling point | 122 °C(lit.) |
| Density | 1.431 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.443(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-(trifluoromethyl)phenol used for?
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2-Fluoro-3-(trifluoromethyl)phenol is primarily used as a building block in organic synthesis, particularly for creating fluorinated compounds relevant to pharmaceutical and agrochemical research and development.
What are the CAS number and chemical formula for this compound?
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The CAS number for 2-Fluoro-3-(trifluoromethyl)phenol is 207291-85-8, and its chemical formula is C6H3(CF3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-(trifluoromethyl)phenol with a purity of at least 97%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should 2-Fluoro-3-(trifluoromethyl)phenol be handled safely?
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2-Fluoro-3-(trifluoromethyl)phenol is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used when handling this compound. Refer to the Safety Data Sheet for detailed handling procedures.
Is 2-Fluoro-3-(trifluoromethyl)phenol a controlled substance?
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Based on the provided data, there is no indication that 2-Fluoro-3-(trifluoromethyl)phenol is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-3-(trifluoromethyl)phenol. We adhere to all relevant shipping and export regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample of 2-Fluoro-3-(trifluoromethyl)phenol, please contact our sales department through the channels provided on the Tech Serve Solutions website.
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