2-Fluoro-3-(trifluoromethyl)phenylacetic acid
2-Fluoro-3-(trifluoromethyl)phenylacetic acid (CAS: 194943-83-4) is a fluorinated organic building block with the molecular formula FC6H3(CF3)CH2CO2H and a molecular weight of 222.14 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for researchers developing novel pharmaceutical candidates and advanced materials. Its specific structure, featuring both fluorine and trifluoromethyl groups on an aromatic ring, offers unique reactivity for custom chemical synthesis and drug discovery.

Pharmaceutical Intermediate
This compound is utilised as a key building block in the synthesis of complex pharmaceutical agents. The presence of fluorine and trifluoromethyl groups can impart desirable pharmacokinetic and pharmacodynamic properties to drug molecules.
Agrochemical Research
It can be employed in the development of new agrochemicals, where fluorinated moieties often contribute to enhanced biological activity and stability.
Materials Science
The unique electronic and structural properties conferred by the fluoro- and trifluoromethyl substituents make it a potential component in the synthesis of specialised polymers or advanced materials.
Custom Synthesis
As a versatile building block, it is suitable for bespoke chemical synthesis projects requiring precisely functionalised aromatic compounds.
| Molecular weight | 222.14 |
|---|---|
| Linear formula | FC6H3(CF3)CH2CO2H |
| Assay | 98% |
| Melting point | 113-116 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-(trifluoromethyl)phenylacetic acid used for?
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2-Fluoro-3-(trifluoromethyl)phenylacetic acid (CAS: 194943-83-4) is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It is a valuable building block for introducing specific fluorinated motifs into target molecules.
What is the CAS number and formula for 2-Fluoro-3-(trifluoromethyl)phenylacetic acid?
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The CAS number is 194943-83-4, and the molecular formula is FC6H3(CF3)CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-(trifluoromethyl)phenylacetic acid with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Fluoro-3-(trifluoromethyl)phenylacetic acid be handled?
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This compound is classified as an irritant. When handling, it is essential to avoid breathing dust, ensure adequate ventilation, and use appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-3-(trifluoromethyl)phenylacetic acid.
How can I request a sample or quote?
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Please contact our sales team directly via the website or by phone to request a sample or a quotation for 2-Fluoro-3-(trifluoromethyl)phenylacetic acid.
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