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2-Fluoro-3-(trifluoromethyl)phenylacetic acid

CAS 194943-83-4FC6H3(CF3)CH2CO2HChemical Synthesis

2-Fluoro-3-(trifluoromethyl)phenylacetic acid (CAS: 194943-83-4) is a fluorinated organic building block with the molecular formula FC6H3(CF3)CH2CO2H and a molecular weight of 222.14 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for researchers developing novel pharmaceutical candidates and advanced materials. Its specific structure, featuring both fluorine and trifluoromethyl groups on an aromatic ring, offers unique reactivity for custom chemical synthesis and drug discovery.

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2-Fluoro-3-(trifluoromethyl)phenylacetic acid (FC6H3(CF3)CH2CO2H) — chemical structure, CAS 194943-83-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC8-C12Carbonyl CompoundsCarboxylic AcidsChemical SynthesisFluorinated Building BlocksOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediate

This compound is utilised as a key building block in the synthesis of complex pharmaceutical agents. The presence of fluorine and trifluoromethyl groups can impart desirable pharmacokinetic and pharmacodynamic properties to drug molecules.

Agrochemical Research

It can be employed in the development of new agrochemicals, where fluorinated moieties often contribute to enhanced biological activity and stability.

Materials Science

The unique electronic and structural properties conferred by the fluoro- and trifluoromethyl substituents make it a potential component in the synthesis of specialised polymers or advanced materials.

Custom Synthesis

As a versatile building block, it is suitable for bespoke chemical synthesis projects requiring precisely functionalised aromatic compounds.

02 /Properties
Molecular weight222.14
Linear formulaFC6H3(CF3)CH2CO2H
Assay98%
Melting point113-116 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
194943-83-4
MDL number
MFCD00061185
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Fluoro-3-(trifluoromethyl)phenylacetic acid used for?

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2-Fluoro-3-(trifluoromethyl)phenylacetic acid (CAS: 194943-83-4) is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It is a valuable building block for introducing specific fluorinated motifs into target molecules.

What is the CAS number and formula for 2-Fluoro-3-(trifluoromethyl)phenylacetic acid?

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The CAS number is 194943-83-4, and the molecular formula is FC6H3(CF3)CH2CO2H.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Fluoro-3-(trifluoromethyl)phenylacetic acid with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should 2-Fluoro-3-(trifluoromethyl)phenylacetic acid be handled?

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This compound is classified as an irritant. When handling, it is essential to avoid breathing dust, ensure adequate ventilation, and use appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.

Is this product available for export?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-3-(trifluoromethyl)phenylacetic acid.

How can I request a sample or quote?

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Please contact our sales team directly via the website or by phone to request a sample or a quotation for 2-Fluoro-3-(trifluoromethyl)phenylacetic acid.

Need 2-Fluoro-3-(trifluoromethyl)phenylacetic acid in a specific grade or volume?