2-Fluoro-3-(trifluoromethyl)benzonitrile
2-Fluoro-3-(trifluoromethyl)benzonitrile (CAS 146070-35-1) is a fluorinated organic building block with the molecular formula C<sub>8</sub>H<sub>3</sub>F<sub>4</sub>N and a molecular weight of 189.11 g/mol. This compound features both a nitrile and a trifluoromethyl group on a fluorinated benzene ring, making it a valuable intermediate in organic synthesis. It is primarily utilised in the development of novel materials and as a precursor in the synthesis of complex organic molecules, particularly within the pharmaceutical and agrochemical sectors.
- IUPAC
- α,α,α,2-Tetrafluoro-m-tolunitrile
- Synonyms
- α,α,α,2-Tetrafluoro-m-tolunitrile
Pharmaceutical Intermediate
Utilised as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique fluorinated structure can impart desirable properties to drug candidates.
Agrochemical Synthesis
Serves as a precursor for the development of new pesticides and herbicides. The incorporation of fluorine often enhances the efficacy and metabolic stability of agrochemicals.
Material Science
Employed in the synthesis of advanced materials where its specific electronic and structural properties can be advantageous. This includes applications in polymers and functional dyes.
Research and Development
A versatile reagent for academic and industrial research laboratories engaged in exploring new synthetic pathways and molecular architectures.
| Molecular weight | 189.11 |
|---|---|
| Linear formula | CF3C6H3(F)CN |
| Assay | 98% |
| Density | 1.323 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4495(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-(trifluoromethyl)benzonitrile used for?
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2-Fluoro-3-(trifluoromethyl)benzonitrile is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. It is also valuable in general organic synthesis and research and development.
What is the CAS number and formula for 2-Fluoro-3-(trifluoromethyl)benzonitrile?
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The CAS number is 146070-35-1, and the molecular formula is C<sub>8</sub>H<sub>3</sub>F<sub>4</sub>N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-(trifluoromethyl)benzonitrile with an assay of 98%. This product is intended for technical and research use; TSS does not represent it as USP, BP, or EP grade.
How should 2-Fluoro-3-(trifluoromethyl)benzonitrile be handled?
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Handle with appropriate personal protective equipment, including eyeshields, face shield, gloves, and a suitable respirator (e.g., type ABEK). Ensure good ventilation. Avoid inhalation of vapours, ingestion, and contact with skin and eyes. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation with potential respiratory irritation.
How is 2-Fluoro-3-(trifluoromethyl)benzonitrile packed and shipped?
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This chemical is shipped according to transport regulations, identified as NA 1993 / PGIII. Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or a sample of 2-Fluoro-3-(trifluoromethyl)benzonitrile, please contact our sales team through the website or via direct enquiry, providing your specific requirements.
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