2-Fluoro-3-(trifluoromethyl)aniline
2-Fluoro-3-(trifluoromethyl)aniline (CAS: 123973-25-1) is a fluorinated organic building block with the molecular formula FC6H3(CF3)NH2 and a molecular weight of 179.11 g/mol. This compound serves as a valuable intermediate in chemical synthesis, particularly for the introduction of trifluoromethyl and fluorine moieties into complex molecules. Its applications span various sectors, including pharmaceuticals and agrochemicals, where precise molecular structures are paramount for biological activity.
- IUPAC
- 3-Amino-2-fluorobenzotrifluoride,α,α,α,2-Tetrafluoro-m-toluidine
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the incorporation of fluorinated groups can enhance metabolic stability and bioavailability. Its unique structure makes it suitable for developing novel drug candidates.
Agrochemical Synthesis
Serves as a building block for the creation of advanced agrochemicals, such as herbicides and insecticides. The trifluoromethyl group can significantly influence the efficacy and spectrum of activity of these crop protection agents.
Material Science
Incorporated into the development of specialised polymers and materials. The presence of fluorine atoms can impart unique properties like thermal stability and chemical resistance to the final products.
Organic Synthesis Research
A key reagent in academic and industrial research laboratories for exploring new synthetic pathways and developing novel fluorinated compounds. Its reactivity profile allows for diverse chemical transformations.
| Molecular weight | 179.11 |
|---|---|
| Linear formula | FC6H3(CF3)NH2 |
| Assay | 97% |
| Boiling point | 189 °C(lit.) |
| Density | 1.39 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.462(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-(trifluoromethyl)aniline used for?
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2-Fluoro-3-(trifluoromethyl)aniline is primarily used as an intermediate in organic synthesis for the production of pharmaceuticals, agrochemicals, and advanced materials. It is also employed in chemical research and development.
What are the CAS number and formula for 2-Fluoro-3-(trifluoromethyl)aniline?
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The CAS number for 2-Fluoro-3-(trifluoromethyl)aniline is 123973-25-1, and its molecular formula is FC6H3(CF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-(trifluoromethyl)aniline with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this compound?
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This compound is classified with GHS07, a Warning signal word, and carries hazard statements including H302, H312, H315, H319, H332, and H335. Recommended personal protective equipment includes eyeshields, face shields, and appropriate gloves and respirator filters (e.g., type ABEK). Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
Is 2-Fluoro-3-(trifluoromethyl)aniline available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Fluoro-3-(trifluoromethyl)aniline. We handle international shipments according to all relevant regulations.
How can I request a quote or sample?
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To request a quote or sample of 2-Fluoro-3-(trifluoromethyl)aniline, please contact our sales team through the website or by calling our customer service line. We are happy to assist with your specific requirements.
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