2-Fluoro-3-(tributylstannyl)pyridine
2-Fluoro-3-(tributylstannyl)pyridine (CAS: 155533-81-6) is an organotin compound with the molecular formula C17H30FNSn and a molecular weight of 386.14 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly for introducing the 2-fluoro-3-pyridyl moiety into complex molecules through cross-coupling reactions. Its utility spans research and development within the fine chemical and pharmaceutical sectors.
Organometallic Reagent in Synthesis
2-Fluoro-3-(tributylstannyl)pyridine acts as a key organometallic reagent. It is employed in Stille coupling reactions and other palladium-catalysed cross-couplings to form new carbon-carbon bonds.
Fluoropyridine Moiety Introduction
This compound is utilised for the efficient incorporation of the 2-fluoro-3-pyridyl fragment into target organic molecules. This structural motif is of interest in medicinal chemistry and materials science.
Research and Development
Primarily used in academic and industrial research laboratories for the synthesis of novel chemical entities and the exploration of new synthetic methodologies involving organotin chemistry.
| Molecular weight | 386.14 |
|---|---|
| Empirical formula | C17H30FNSn |
| Assay | 97% |
| Density | 1.176 g/mL at 25 °C |
| Refractive index | n20/D 1.508 |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H372Causes damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P314Get medical attention if you feel unwell
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2788 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 21-25-36/38-48/23/25-50/53 |
| Safety statements (S) | 35-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-(tributylstannyl)pyridine used for?
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2-Fluoro-3-(tributylstannyl)pyridine is primarily used as an organometallic reagent in organic synthesis, specifically for introducing the 2-fluoro-3-pyridyl group into molecules via cross-coupling reactions.
What is the CAS number and molecular formula for 2-Fluoro-3-(tributylstannyl)pyridine?
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The CAS number is 155533-81-6, and the empirical formula (Hill notation) is C17H30FNSn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-(tributylstannyl)pyridine with a minimum assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Fluoro-3-(tributylstannyl)pyridine be handled safely?
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This compound is dangerous and requires strict safety protocols. It is toxic if swallowed and harmful in contact with skin, causing skin and serious eye irritation, and may cause damage to organs through prolonged or repeated exposure. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator, in a well-ventilated area. Avoid release to the environment.
How is 2-Fluoro-3-(tributylstannyl)pyridine packed, shipped, and exported?
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2-Fluoro-3-(tributylstannyl)pyridine is packed and shipped according to international regulations for hazardous materials, including UN 2788, Class 6.1, Packing Group III. Tech Serve Solutions is an experienced global exporter.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or email our sales department, providing the product name and CAS number (155533-81-6).
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