2′-Deoxyadenosine 5′-diphosphate sodium salt
2′-Deoxyadenosine 5′-diphosphate sodium salt (CAS: 72003-83-9) is a crucial nucleotide derivative with the empirical formula C10H15N5O9P2 · xNa+. Its molecular weight is 411.20 (free acid basis). This compound is primarily utilised in biochemical research for the synthesis of deoxyadenylate oligonucleotides and as an inhibitor for enzymes like bacterial poly(A) polymerase. It also serves as a substrate or inhibitor in studies of ATPase and polymerase specificity.
- IUPAC
- dADP
Oligonucleotide Synthesis
2′-Deoxyadenosine 5′-diphosphate sodium salt can be employed as a substrate for enzymes such as polynucleotide phosphorylase from Escherichia coli, facilitating the synthesis of deoxyadenylate oligonucleotides.
Enzyme Inhibition Studies
This compound acts as an inhibitor of bacterial poly(A) polymerase. It is also used in research to study the specificity of ATPase and DNA and RNA polymerases.
Biochemical Research Reagent
Utilised as a research tool in cell biology and metabolomics, dADP serves as an alternative substrate or inhibitor in various enzymatic assays and pathway investigations.
| Molecular weight | 411.20 (free acid basis) |
|---|---|
| Empirical formula | C10H15N5O9P2 · xNa+ |
| Assay | ≥95% (HPLC) |
| Storage temperature | −20°C |
| Application | 2′-Deoxyadenosine 5′-diphosphate (dADP) may be used for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. dADP is used as an inhibitor of bacterial poly(A) polymerase. DeoxyADP may be use as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity. |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 22-26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Deoxyadenosine 5′-diphosphate sodium salt used for?
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This compound is used for the synthesis of deoxyadenylate oligonucleotides, as an inhibitor of bacterial poly(A) polymerase, and as a substrate or inhibitor in studies of ATPase and DNA/RNA polymerase specificity. It is also relevant in cell biology and metabolomics research.
What are the CAS number and formula for 2′-Deoxyadenosine 5′-diphosphate sodium salt?
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The CAS number is 72003-83-9, and the empirical formula is C10H15N5O9P2 · xNa+.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Deoxyadenosine 5′-diphosphate sodium salt with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2′-Deoxyadenosine 5′-diphosphate sodium salt be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator. It is classified as toxic if swallowed, in contact with skin, or if inhaled, and is a skin and eye irritant. Follow all precautionary statements (P261, P280, P301+P310, P305+P351+P338, P311).
How is this product exported and shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2′-Deoxyadenosine 5′-diphosphate sodium salt, which is typically stored at -20°C and shipped according to international regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample for 2′-Deoxyadenosine 5′-diphosphate sodium salt, please contact our sales team through the TSS website.
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