2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate (CAS: 18423-40-0) is a purine deoxynucleotide with the empirical formula C10H16N5O13P3 · xNa+ · yH2O. Its molecular weight is approximately 507.18 (anhydrous free acid basis). This compound serves as a critical substrate for DNA polymerases and reverse transcriptases, making it essential for molecular biology research, particularly in DNA synthesis and repair studies.
- IUPAC
- dGTP sodium salt hydrate
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DNA Synthesis and Replication Studies
As a fundamental building block for DNA, 2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate is indispensable for in vitro DNA synthesis assays, DNA replication studies, and DNA repair mechanism investigations. Its role as a substrate for DNA polymerases is crucial for understanding these fundamental cellular processes.
Enzyme Kinetics and Mechanism Studies
This dGTP derivative is employed to investigate the kinetics and specificity of various enzymes involved in nucleic acid metabolism. Researchers utilise it to study DNA polymerases, reverse transcriptases, and other nucleotide-processing enzymes.
Molecular Biology Reagent
Utilised in a wide range of molecular biology applications, including PCR, sequencing, and other enzymatic amplification techniques. Its high purity ensures reliable and accurate experimental outcomes in sensitive biological assays.
Metabolomics Research
As a key metabolite, it is relevant in studies concerning metabolic pathways and metabolomics. Understanding its levels and role can provide insights into cellular energy status and nucleotide metabolism.
| Molecular weight | 507.18 (anhydrous free acid basis) |
|---|---|
| Empirical formula | C10H16N5O13P3 · xNa+ · yH2O |
| Assay | ≥96% (HPLC) |
| Storage temperature | −20°C |
| Application | Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity and kinetics of various NTPases and ribonucleotide reductases. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate used for?
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2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate is primarily used as a substrate for DNA polymerases and reverse transcriptases in molecular biology research, including DNA synthesis, replication studies, and enzyme kinetics.
What are the CAS number and formula for this product?
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The CAS number for the anhydrous form is 18423-40-0. The empirical formula is C10H16N5O13P3 · xNa+ · yH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate with an assay of ≥96% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended. Store at -20°C. The product has a WGK rating of 3 in Germany, indicating it is hazardous to water.
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is controlled or scheduled under any regulations.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quote or sample of 2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate.
How is this product packed and exported?
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Tech Serve Solutions specialises in global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents, ensuring appropriate packaging for safe international transit.
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