2′,5′-dd-3′-AMP-bis(t-Bu-SATE)
2′,5′-dd-3′-AMP-bis(t-Bu-SATE) (CAS 387356-12-9) is a chemical compound with the empirical formula C24H38N5O7PS2 and a molecular weight of 603.69 g/mol. This molecule is recognised for its role as an adenylyl cyclase inhibitor. It is primarily utilised in cell biology research for studying cellular signaling pathways and cyclic nucleotide metabolism, particularly concerning G proteins. TSS supplies this research-grade chemical for laboratory applications.
- IUPAC
- 2′,5′-Dideoxyadenosine-3′-O-bis(S-pivaloyl-2-thioethyl)-phosphate
- Synonyms
- 2′,5′-Dideoxyadenosine-3′-O-bis(S-pivaloyl-2-thioethyl)-phosphate

Adenylyl Cyclase Inhibition Studies
This compound serves as a valuable tool in research focused on the inhibition of adenylyl cyclase activity. It aids in understanding the downstream effects of modulating cyclic AMP levels within cells.
Cellular Signaling Research
Utilised in the investigation of complex cellular signaling cascades, particularly those involving G proteins and cyclic nucleotides. It helps researchers elucidate signal transduction pathways.
Cyclic Nucleotide Metabolism Research
Facilitates studies into the metabolism and regulation of cyclic nucleotides like cyclic AMP. Its inhibitory action provides insights into these crucial second messenger systems.
Neuroscience Investigations
Applied in neuroscience research to explore the roles of adenylyl cyclase and cyclic nucleotides in neuronal function and signaling.
| Molecular weight | 603.69 |
|---|---|
| Empirical formula | C24H38N5O7PS2 |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: soluble5 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,5′-dd-3′-AMP-bis(t-Bu-SATE) used for?
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2′,5′-dd-3′-AMP-bis(t-Bu-SATE) is primarily used in research for studying adenylyl cyclase inhibition, cellular signaling, cyclic nucleotide metabolism, and in neuroscience investigations.
What are the CAS number and empirical formula for 2′,5′-dd-3′-AMP-bis(t-Bu-SATE)?
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The CAS number is 387356-12-9 and the empirical formula is C24H38N5O7PS2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′,5′-dd-3′-AMP-bis(t-Bu-SATE) with a purity of ≥98% (HPLC). It is supplied as a research-grade chemical and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling requirements for this chemical?
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Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (half-mask respirator EU/US, or multi-purpose combination cartridge US), should be used. This compound has a WGK Germany rating of 3, indicating a high hazard to water.
How is 2′,5′-dd-3′-AMP-bis(t-Bu-SATE) stored and shipped?
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The chemical should be stored at −20°C. TSS exports fine chemicals globally, adhering to all relevant shipping and regulatory requirements.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone. Our specialists will be pleased to assist you.
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