(S)-(−)-1,2-Diaminopropane dihydrochloride
(S)-(−)-1,2-Diaminopropane dihydrochloride (CAS: 19777-66-3) is a chiral organic building block with the linear formula CH3CH(NH2)CH2NH2·2HCl and a molecular weight of 147.05 g/mol. Supplied at a purity of 99%, this compound is a valuable intermediate in asymmetric synthesis, particularly for the preparation of chiral imidazolines. Its specific optical activity is [α]22/D −4°, c = 20 in H2O.
- IUPAC
- (S)-(−)-Propylenediamine dihydrochloride,(S)-1,2-Propanediamine dihydrochloride
- Synonyms
- (S)-(−)-Propylenediamine dihydrochloride(S)-1,2-Propanediamine dihydrochloride
Synthesis of Chiral Imidazolines
This diamine serves as a key precursor for the synthesis of chiral imidazolines. These compounds are important motifs in asymmetric catalysis and organic synthesis.
Chiral Building Block
As a chiral diamine, it is employed as a versatile building block in the construction of more complex chiral molecules. Its defined stereochemistry is crucial for enantioselective synthesis.
Organic Synthesis Intermediate
Utilised in various organic synthesis pathways, this compound contributes to the development of novel organic compounds and pharmaceutical intermediates.
| Molecular weight | 147.05 |
|---|---|
| Linear formula | CH3CH(NH2)CH2NH2·2HCl |
| Assay | 99% |
| Optical activity | [α]22/D −4°, c = 20 in H2O |
| Application | This diamine has been used for the synthesis of chiral imidazolines.1,2 |
| Melting point | 227-229 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1,2-Diaminopropane dihydrochloride used for?
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(S)-(−)-1,2-Diaminopropane dihydrochloride is primarily used in asymmetric synthesis, particularly for the preparation of chiral imidazolines and as a general chiral building block in organic synthesis.
What is the CAS number and formula for (S)-(−)-1,2-Diaminopropane dihydrochloride?
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The CAS number is 19777-66-3 and its linear formula is CH3CH(NH2)CH2NH2·2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-1,2-Diaminopropane dihydrochloride with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should (S)-(−)-1,2-Diaminopropane dihydrochloride be handled?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation. P261 (Avoid breathing dust), P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).
Is (S)-(−)-1,2-Diaminopropane dihydrochloride a controlled substance?
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The provided data does not indicate that (S)-(−)-1,2-Diaminopropane dihydrochloride is a controlled substance.
How can I request a sample or quote?
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To request a sample or quote for (S)-(−)-1,2-Diaminopropane dihydrochloride, please contact our sales team through the website or by phone.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. (S)-(−)-1,2-Diaminopropane dihydrochloride is packed and shipped according to international regulations for hazardous materials.
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