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(S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol

CAS 140408-82-8C22H21NOChemical Synthesis

(S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol (CAS: 140408-82-8), with the molecular formula C22H21NO and a molecular weight of 315.41 g/mol, is a chiral building block used in asymmetric synthesis. Its specific stereochemistry makes it valuable for creating enantiomerically pure compounds. This heterocyclic compound serves as a key intermediate in complex organic synthesis and the development of novel chemical entities.

Synonyms
4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol140408-82-8C22H21NO
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(S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol (C22H21NO) — chemical structure, CAS 140408-82-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksIsoquinolines
01 /Applications

Asymmetric Synthesis

This chiral isoquinoline derivative is employed as a building block in stereoselective synthesis. It enables the construction of complex molecules with defined stereochemistry, crucial for pharmaceutical research and development.

Chiral Auxiliary

The compound can function as a chiral auxiliary, influencing the stereochemical outcome of reactions. Its application helps in obtaining specific enantiomers of target molecules with high optical purity.

Organic Synthesis Intermediate

As a heterocyclic building block, it is used in the synthesis of more complex organic structures. Its unique diphenylmethanol moiety offers specific reactivity profiles for various transformations.

02 /Properties
Molecular weight315.41
Empirical formulaC22H21NO
Assay97%
Optical activity[α]22/D −100°, c = 1 in methanol
Melting point104-107 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
140408-82-8
MDL number
MFCD01863584
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol used for?

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It is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis.

What are the CAS number and molecular formula?

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The CAS number is 140408-82-8, and the molecular formula is C22H21NO.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product at an assay of 97%. We do not represent it as USP, BP, EP, or any pharmacopoeia grade.

How should (S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol be handled?

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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is a skin, eye, and respiratory irritant.

Is this product available for export?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be exported.

How can I request a sample or a quote?

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Please contact our sales department or use the online inquiry form on our website to request a sample or a quote for (S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol.

Need (S)-(−)-1,2,3,4-Tetrahydro-α,α-diphenyl-3-isoquinolinemethanol in a specific grade or volume?