4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid
4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid (CAS: 182281-01-2, C11H15BO4) is a versatile aryl boronic acid derivative. Its structure features a tetrahydropyranyl (THP) protected phenol, making it a useful building block in organic synthesis. This compound is primarily employed in cross-coupling reactions, such as Suzuki-Miyaura couplings, for the construction of complex organic molecules, particularly in pharmaceutical research and development.

Suzuki-Miyaura Coupling Reagent
Serves as a key coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. This is crucial for synthesising biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate
Utilised in the synthesis pathways for novel drug candidates. The protected phenol moiety allows for selective functionalization and subsequent deprotection in multi-step syntheses.
Organic Synthesis Building Block
A valuable reagent for introducing a substituted phenylboronic acid moiety into target molecules. Its THP protecting group offers stability under various reaction conditions.
| Molecular weight | 222.05 |
|---|---|
| Empirical formula | C11H15BO4 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid used for?
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This compound is primarily used as a building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in pharmaceutical research and development.
What is the CAS number and formula for 4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid?
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The CAS number is 182281-01-2 and the empirical formula is C11H15BO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research grade product. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for this product?
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This compound is classified under WGK Germany 3, indicating it is hazardous to water. Appropriate personal protective equipment (PPE) should be worn, and it should be handled in a well-ventilated area, avoiding contact with skin, eyes, and clothing.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid.
How can I request a quote or sample?
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To request a quote or sample of 4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid, please contact our sales team through the website or via the provided contact details.
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