4-(Thiophen-2-yl)aniline
4-(Thiophen-2-yl)aniline (CAS 70010-48-9), with the molecular formula C10H9NS and a molecular weight of 175.25 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis, particularly within the fields of materials science and pharmaceutical research. Its structure incorporates both an aniline and a thiophene moiety, enabling diverse chemical transformations and applications in the development of novel organic molecules and functional materials.
- IUPAC
- 4-(2-Thienyl)aniline
- Synonyms
- 4-(2-Thienyl)aniline

Organic Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of more complex organic molecules. Its reactive amine and thiophene groups allow for various coupling reactions, derivatisation, and heterocyclic ring formations.
Materials Science Research
The molecule's structural features, including the thiophene ring, make it a potential precursor for organic electronic materials, such as conductive polymers or organic semiconductors.
Pharmaceutical and Agrochemical Development
As a building block, 4-(Thiophen-2-yl)aniline can be incorporated into the development pathways for new pharmaceutical agents or agrochemicals, leveraging its unique heterocyclic structure.
| Molecular weight | 175.25 |
|---|---|
| Empirical formula | C10H9NS |
| Assay | 97% |
| Melting point | 74-78 °C |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Thiophen-2-yl)aniline used for?
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4-(Thiophen-2-yl)aniline is primarily used as a building block in organic synthesis, with applications in materials science, and in the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 4-(Thiophen-2-yl)aniline?
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The CAS number is 70010-48-9 and the chemical formula is C10H9NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Thiophen-2-yl)aniline with a minimum assay of 97%. This product is supplied for laboratory and research purposes and is not represented as USP, BP, EP, or any pharmacopoeia grade.
How should 4-(Thiophen-2-yl)aniline be handled safely?
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This compound is classified as Danger. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Appropriate personal protective equipment including a dust mask (N95), eye shields, face shields, and gloves should be worn. Handle in a well-ventilated area.
Is 4-(Thiophen-2-yl)aniline a controlled substance?
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Based on the provided data, 4-(Thiophen-2-yl)aniline is not indicated as a controlled substance. However, users should always verify local regulations.
How is 4-(Thiophen-2-yl)aniline typically packed and shipped?
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This chemical is shipped under UN 2811, Class 6.1, Packing Group III. Packaging adheres to international shipping regulations for hazardous materials.
How can I request a sample or quote for 4-(Thiophen-2-yl)aniline?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via our website or direct email, providing your specific requirements and delivery details.
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