4-(Succinylamino)phenylboronic acid pinacol ester
4-(Succinylamino)phenylboronic acid pinacol ester (CAS 480424-98-4), with the molecular formula C16H22BNO5 and a molecular weight of 319.16, is a valuable organoboron compound. It functions as a building block in organic synthesis, particularly in cross-coupling reactions. Its structure facilitates the introduction of substituted phenyl groups into complex molecules, making it relevant for the development of pharmaceuticals and advanced materials.
- IUPAC
- N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]succinamic acid
- Synonyms
- N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]succinamic acid
Suzuki-Miyaura Coupling Reagent
This boronate ester is employed as a coupling partner in Suzuki-Miyaura reactions. It allows for the efficient formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate Synthesis
It serves as a key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its aryl boronate functionality is crucial for constructing complex molecular scaffolds found in various drug candidates.
Materials Science Research
The compound can be utilised in the development of novel organic materials. Its incorporation into polymer backbones or small molecules may impart specific electronic or optical properties for advanced applications.
Chemical Synthesis Building Block
As a versatile organometallic reagent, it is used in diverse synthetic strategies within academic and industrial research laboratories. Its reactivity profile enables its use in a broad range of transformations.
| Molecular weight | 319.16 |
|---|---|
| Empirical formula | C16H22BNO5 |
| Assay | 97% |
| Melting point | 175-178 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Succinylamino)phenylboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds and the synthesis of complex organic molecules, including pharmaceutical intermediates and materials.
What are the CAS number and molecular formula for 4-(Succinylamino)phenylboronic acid pinacol ester?
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The CAS number is 480424-98-4, and the molecular formula is C16H22BNO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 97%. This is a research-grade chemical, and we do not represent it as USP, BP, EP, or pharmacopoeia grade.
How should 4-(Succinylamino)phenylboronic acid pinacol ester be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation).
Is this compound shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team directly through the website to request a quote or a sample of 4-(Succinylamino)phenylboronic acid pinacol ester.
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