Hexafluoropropylene oxide
Hexafluoropropylene oxide (CAS: 428-59-1, C3F6O) is a fluorinated epoxide with a molecular weight of 166.02 g/mol. This compound serves as a critical building block in advanced chemical synthesis. It is particularly noted for its utility in creating fluorine-containing polymers for specialized applications, including those in microelectronics and advanced materials science. Its unique chemical structure enables the development of materials with enhanced properties.
- IUPAC
- Hexafluoro-1,2-epoxypropane

Fluoropolymer Synthesis
Hexafluoropropylene oxide is a key monomer in the synthesis of fluoropolymers. These polymers possess unique properties such as chemical resistance, thermal stability, and low surface energy, making them suitable for demanding industrial applications.
Advanced Materials
Its incorporation into polymer chains contributes to materials with tailored properties for applications in electronics and specialty coatings. This includes use in developing resists for photolithography processes.
Chemical Intermediates
As a reactive epoxide, it functions as a versatile intermediate in the synthesis of various complex organic molecules and fluorinated compounds.
Specialty Gases and Reagents
Hexafluoropropylene oxide is categorised as a specialty gas and a synthetic reagent, essential for research and development in fluorine chemistry and related fields.
| Molecular weight | 166.02 |
|---|---|
| Empirical formula | C3F6O |
| Assay | 98% |
| Boiling point | −42 °C(lit.) |


Hazard statements
- H280Contains gas under pressure; may explode if heated
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P410Protect from sunlight
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 1956 2.2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-44 |
| Safety statements (S) | 7-26-37/39-38 |
| Supplemental hazards | Risk of explosion if heated under confinement. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hexafluoropropylene oxide used for?
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Hexafluoropropylene oxide is used in advanced chemical synthesis, particularly for creating fluorine-containing polymers for applications in microelectronics, advanced materials, and as a chemical intermediate.
What are the CAS number and formula for Hexafluoropropylene oxide?
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The CAS number for Hexafluoropropylene oxide is 428-59-1, and its molecular formula is C3F6O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hexafluoropropylene oxide with an assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Hexafluoropropylene oxide be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation. It is labelled with Hazard Statements H280 (contains gas under pressure; may explode if heated under confinement), H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Risk of explosion if heated under confinement.
How is Hexafluoropropylene oxide packed, shipped, and exported?
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Hexafluoropropylene oxide is supplied as a gas under pressure (UN 1956 2.2) and is exported globally by Tech Serve Solutions in compliance with all relevant transport regulations.
How can I request a quote or sample for Hexafluoropropylene oxide?
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To request a quote or sample for Hexafluoropropylene oxide, please contact the Tech Serve Solutions sales team via our website or by phone.
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