4′-Piperidinoacetophenone
4′-Piperidinoacetophenone (CAS: 10342-85-5) is a chemical compound with the formula C13H17NO and a molecular weight of 203.28 g/mol. Supplied by Tech Serve Solutions with an assay of 97%, this compound serves as a valuable building block in chemical synthesis. Its applications include its use as an internal standard in analytical methods for pharmaceuticals, contributing to the precise determination of active pharmaceutical ingredients in various matrices.
- IUPAC
- 1-[4-(1-Piperidinyl)]phenyl]ethanone
- Synonyms
- 1-[4-(1-Piperidinyl)]phenyl]ethanone

Analytical Standard
4′-Piperidinoacetophenone has been utilised as an internal standard in gas chromatography-tandem mass spectrometry. This application is crucial for the accurate determination of pharmaceutical compounds, such as pethidine, in biological fluids.
Chemical Synthesis Intermediate
As a key building block, this compound is employed in complex organic synthesis pathways. Its structure, featuring a piperidine ring and an acetophenone moiety, makes it suitable for the construction of diverse molecular architectures.
Research and Development
The compound is frequently used in research laboratories for exploring new synthetic routes and developing novel compounds with potential pharmaceutical or material science applications. Its availability supports innovation in chemical sciences.
| Molecular weight | 203.28 |
|---|---|
| Empirical formula | C13H17NO |
| Assay | 97% |
| Application | 4′-Piperidinoacetophenone was used as internal standard in the determination of pethidine, a narcotic analgesic drug in body fluids by gas chromatography-tandem mass spectrometry1. |
| Melting point | 85-87 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Piperidinoacetophenone used for?
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4′-Piperidinoacetophenone is primarily used as an internal standard in analytical chemistry for the determination of drugs like pethidine in body fluids and as a building block in chemical synthesis.
What is the CAS number and formula for 4′-Piperidinoacetophenone?
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The CAS number for 4′-Piperidinoacetophenone is 10342-85-5, and its molecular formula is C13H17NO.
What grade and purity does Tech Serve Solutions supply for 4′-Piperidinoacetophenone?
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Tech Serve Solutions supplies 4′-Piperidinoacetophenone with an assay of 97%. This is a technical grade suitable for chemical synthesis and research applications; it is not represented as USP, BP, or EP grade.
What are the primary hazards associated with 4′-Piperidinoacetophenone?
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4′-Piperidinoacetophenone is classified with the signal word 'Warning' and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyesshields, and gloves, should be used.
Is 4′-Piperidinoacetophenone a controlled substance?
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The provided data does not indicate that 4′-Piperidinoacetophenone is a controlled substance.
How is 4′-Piperidinoacetophenone packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals with adherence to all relevant safety and transport regulations. Specific packaging details are available upon request.
How can I request a sample or quote for 4′-Piperidinoacetophenone?
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To request a sample or quote for 4′-Piperidinoacetophenone, please contact our sales department through the channels provided on the Tech Serve Solutions website.
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