Tri-sec-butylborane solution

CAS 1113-78-6[C2H5CH(CH3)]3BChemical Synthesis

Tri-sec-butylborane solution (CAS: 1113-78-6; Formula: [C2H5CH(CH3)]3B) is a borane compound offered by Tech Serve Solutions. With a molecular weight of 182.15 g/mol, this organoboron reagent is supplied as a 1.0 M solution in tetrahydrofuran (THF). It serves as a valuable catalyst and reagent in various organic synthesis applications, particularly in reduction and polymerization processes.

IUPAC: Tris(1-methylpropyl)borane
Synonyms: Tris(1-methylpropyl)borane

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Tri-sec-butylborane solution ([C2H5CH(CH3)]3B) — chemical structure, CAS 1113-78-6; Chemistry, fine chemical supplied by Tech Serve Solutions

BoranesChemical SynthesisReductionSynthetic Reagents

01 /Applications

Catalyst for Allylic Alkylations

Tri-sec-butylborane solution facilitates allylic alkylations, a key reaction for the synthesis of unsaturated aldehydes and alcohols. This application is crucial in constructing complex organic molecules with specific functional groups.

Cis-Addition Reactions

This reagent promotes the cis-addition of carbon-hydrogen bonds from pyrroles and thiophenes to alkynes. This reaction is important for creating specific stereochemical outcomes in heterocyclic chemistry.

Borane-Induced Reductions

It acts as a reagent in borane-induced radical reduction of alkenyl and alkynyliodanes. This process is useful for the selective reduction of unsaturated organic compounds.

Polymerization Initiation

Tri-sec-butylborane solution is employed to initiate polymerization reactions, leading to the synthesis of polymethylenes and ethylene-propylene copolymers. This is vital in materials science and polymer chemistry.

Asymmetric Synthesis

The compound finds use in asymmetric synthesis, including the preparation of vinylglycidols and the asymmetric addition of alcohols to vinyl epoxides, enabling the creation of enantiomerically enriched products.

02 /Properties

Molecular weight	182.15
Linear formula	[C2H5CH(CH3)]3B
Density	0.799 g/mL at 25 °C
Concentration	1.0 M in THF
Application	Catalyst for: • Allylic alkylations for synthesis of unsaturated aldehydes and alcohols1• Cis-addition of carbon-hydrogen bonds of pyrroles and thiophenes to alkynes2• Borane-induced radical reduction of alkenyl and alkynyliodanes3• Initiating polymerization for synthesis of polymethylenes and ethylene-propylene4• Asymmetric synthesis of vinylglycidols5• Asymmetric addition of alcohols to vinyl epoxides6

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H225Highly flammable liquid and vapour
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements

P210Keep away from heat, sparks and open flames. No smoking
P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Flash point	-17 °C / 1.4 °F
Transport (UN / ADR)	UN 2924 8(3) / PGII
Water hazard class (WGK, DE)	1
Hazard codes (EU)	F,C
Risk statements (R)	11-19-34-37-40
Safety statements (S)	16-26-36/37/39-45
Supplemental hazards	May form explosive peroxides.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1113-78-6

MDL number

MFCD00009325

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tri-sec-butylborane solution used for?

Tri-sec-butylborane solution (CAS: 1113-78-6) is primarily used as a catalyst and reagent in organic synthesis. Its applications include allylic alkylations, cis-addition reactions, borane-induced reductions, polymerization initiation, and asymmetric synthesis.

What are the CAS number and formula for Tri-sec-butylborane solution?

The CAS number for Tri-sec-butylborane solution is 1113-78-6, and its linear formula is [C2H5CH(CH3)]3B.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tri-sec-butylborane solution as a 1.0 M solution in THF. This is a technical/research grade product, and TSS does not represent it as USP, BP, or EP grade.

What are the safety and handling precautions for Tri-sec-butylborane solution?

Tri-sec-butylborane solution is a Danger hazard, flammable, corrosive, and may cause respiratory irritation and is suspected of causing cancer (H225-H314-H335-H351). It may also form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for full details.

How is Tri-sec-butylborane solution packed, shipped, and exported?

Tri-sec-butylborane solution is typically packed in appropriate containers for hazardous materials, considering its flammability and corrosivity. It is shipped and exported in compliance with international regulations for dangerous goods, such as UN 2924, Class 8(3), Packing Group II.

How can I request a sample or quote for Tri-sec-butylborane solution?

To request a sample or quote for Tri-sec-butylborane solution, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.