2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite (CAS: 102691-36-1) is a phosphorus-containing organic compound with the linear formula {[(CH3)2CH]2N}2POCH2CH2CN and a molecular weight of 301.41 g/mol. This phosphoramidite serves as a valuable building block in organic synthesis, particularly in the preparation of more complex phosphorus-containing molecules. Its specific structure lends itself to various applications within chemical research and development.
- IUPAC
- Bis(diisopropylamino)(2-cyanoethoxy)phosphine
- Synonyms
- N′-tetraisopropylphosphordiamidite, {[(CH3)2CH]2N}2POCH2CH2CN, Bis(diisopropylamino)(2-cyanoethoxy)phosphine

Phosphorus Chemistry Reagent
Utilised as a key intermediate in the synthesis of novel phosphorus compounds. Its reactivity allows for the introduction of phosphorodiamidite moieties into target molecules.
Organic Synthesis Building Block
Serves as a versatile building block in the construction of complex organic structures. It is employed in research and development settings for creating new chemical entities.
Precursor for Specialty Chemicals
Can be used as a precursor in the development of specialty chemicals requiring specific phosphorus functionalities. Its application is relevant in the fine chemical sector.
| Molecular weight | 301.41 |
|---|---|
| Linear formula | {[(CH3)2CH]2N}2POCH2CH2CN |
| Assay | ≥98.0% (31P-NMR) |
| Boiling point | 100 °C/0.5 mmHg(lit.) |
| Density | 0.949 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.470(lit.)n20/D 1.470 |
| Storage temperature | 2-8°C |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/38-42/43 |
| Safety statements (S) | 3-23-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite used for?
+
This compound is primarily used as a building block in organic synthesis and as a reagent in phosphorus chemistry for the preparation of more complex phosphorus-containing molecules.
What are the CAS number and formula for this product?
+
The CAS number is 102691-36-1 and the linear formula is {[(CH3)2CH]2N}2POCH2CH2CN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product with an assay of ≥98.0% (31P-NMR). It is supplied as a research or technical grade chemical and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite be handled safely?
+
This compound is flammable (flash point 60 °C) and poses hazards including skin and eye irritation, and potential respiratory or skin sensitisation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is this chemical packed, shipped, and exported?
+
As an experienced global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and adheres to all regulations for the safe shipment and international export of this chemical.
How can I request a sample or a quote for 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite?
+
To request a sample or a quote, please contact our sales department via the website or through the provided contact details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis