2-Cyanobenzoic acid
2-Cyanobenzoic acid (CAS: 3839-22-3), with the formula C8H5NO2 and a molecular weight of 147.13 g/mol, is an organic compound typically supplied as technical grade by Tech Serve Solutions. It serves as a key reactant in various synthetic pathways, notably in the development of novel oxazolidinone derivatives and as a precursor for JAK2 inhibitors. Its applications extend to decarboxylation and halogenation reactions within chemical synthesis.
- IUPAC
- o-Carboxybenzonitrile,NSC 193443
- Synonyms
- o-Carboxybenzonitrile2-CarboxybenzonitrileBenzonitrile, 2-carboxy-
Synthesis of T-Box Riboswitch Derivatives
2-Cyanobenzoic acid is a crucial reactant in the preparation of T-box riboswitch antiterminator RNA-binding oxazolidinone derivatives, contributing to advancements in molecular biology tools.
Preparation of Modified Cyclodextrins
This compound is utilised in the synthesis of benzoate-modified beta-cyclodextrin derivatives, which may find applications in areas requiring specialised host-guest chemistry.
Development of JAK2 Inhibitors
It acts as a reactant in the synthesis of pyrrolo[1,2-f]triazines, a class of compounds investigated for their potential as JAK2 inhibitors in pharmaceutical research.
Decarboxylation Reactions
2-Cyanobenzoic acid participates in fundamental organic transformations, including decarboxylation reactions, enabling the removal of a carboxyl group during synthesis.
Decarboxylative Halogenation
The compound is employed in decarboxylative halogenation processes, allowing for the simultaneous introduction of a halogen and removal of a carboxyl group.
| Molecular weight | 147.13 |
|---|---|
| Linear formula | NCC6H4CO2H |
| Grade | technical grade |
| Application | Reactant involved in the synthesis of:• T-box riboswitch antiterminator RNA-binding oxazolidinone derivatives1• Benzoate modified β-cyclodextrin derivatives2• Pyrrolo[1,2-f]triazines for use as JAK2 inhibitors3Reactant involved in:• Decarboxylation4• Decarboxylative halogenation3• Protodecarboxylation5 |
| Melting point | 212 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Cyanobenzoic acid used for?
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2-Cyanobenzoic acid is used as a reactant in the synthesis of oxazolidinone derivatives, benzoate modified beta-cyclodextrin derivatives, and pyrrolo[1,2-f]triazines (potential JAK2 inhibitors). It is also involved in decarboxylation, decarboxylative halogenation, and protodecarboxylation reactions.
What is the CAS number and chemical formula for 2-Cyanobenzoic acid?
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The CAS number is 3839-22-3 and the chemical formula is C8H5NO2 (or NCC6H4CO2H).
What grade and purity does Tech Serve Solutions supply for 2-Cyanobenzoic acid?
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Tech Serve Solutions supplies 2-Cyanobenzoic acid in technical grade. We do not represent this product as USP, BP, or EP grade.
How should 2-Cyanobenzoic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for full details.
How is 2-Cyanobenzoic acid packed, shipped, or exported?
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Products are carefully packed according to international shipping regulations to ensure safe transit. TSS is a global supplier and exporter.
How can I request a quote or sample of 2-Cyanobenzoic acid?
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Please contact our sales team via the website or direct email to request a quote or a sample of 2-Cyanobenzoic acid.
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