2-Bromo-5-fluorobenzoic acid
2-Bromo-5-fluorobenzoic acid (CAS 394-28-5) is a halogenated aromatic carboxylic acid with the molecular formula C6H3Br(F)COOH and a molecular weight of 219.01 g/mol. This compound serves as a valuable intermediate and building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its reactive bromine and carboxylic acid functionalities, coupled with the presence of fluorine, allow for diverse chemical transformations.

Pharmaceutical Intermediate
Utilised in the synthesis of complex active pharmaceutical ingredients (APIs), leveraging its substituted benzoic acid structure for molecular elaboration and the introduction of fluorine atoms.
Agrochemical Synthesis
Serves as a precursor for the development of novel pesticides and herbicides, where fluorinated aromatic compounds often exhibit enhanced biological activity and stability.
Materials Science Research
Employed as a building block for the creation of specialised polymers and functional materials, benefiting from the unique electronic and physical properties imparted by the bromine and fluorine substituents.
Organic Synthesis Reagent
A versatile reagent for introducing the 2-bromo-5-fluorobenzoyl moiety into various organic molecules through standard carboxylic acid derivatisation reactions.
| Molecular weight | 219.01 |
|---|---|
| Linear formula | C6H3Br(F)COOH |
| Assay | 96% |
| Melting point | 154-157 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5-fluorobenzoic acid used for?
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2-Bromo-5-fluorobenzoic acid is primarily used as an intermediate and building block in organic synthesis, particularly for pharmaceuticals, agrochemicals, and materials science research.
What is the CAS number and molecular formula for 2-Bromo-5-fluorobenzoic acid?
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The CAS number is 394-28-5 and the molecular formula is C6H3Br(F)COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-5-fluorobenzoic acid with an assay of 96%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Bromo-5-fluorobenzoic acid be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a type N95 (US) or P1 (EN143) respirator filter if necessary. Refer to the Safety Data Sheet for full details.
Is 2-Bromo-5-fluorobenzoic acid a controlled substance?
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The provided data does not indicate that 2-Bromo-5-fluorobenzoic acid is a controlled substance.
How is 2-Bromo-5-fluorobenzoic acid typically packed and shipped?
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Products are carefully packed according to international standards for safe transport and exported globally by TSS.
How can I request a quote or sample for 2-Bromo-5-fluorobenzoic acid?
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Please contact our sales team or use the online inquiry form on our website to request a quote or sample.
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