2-Bromo-5-fluoroanisole
2-Bromo-5-fluoroanisole (CAS: 450-88-4) is a halogenated aromatic compound with the molecular formula C7H6BrFO and a molecular weight of 205.02 g/mol. This versatile organic building block is primarily utilised in chemical synthesis, particularly in the development of complex organic molecules. Its structure, featuring both bromine and fluorine substituents on an anisole core, makes it a valuable intermediate for introducing specific functionalities in multi-step synthetic pathways.
- IUPAC
- 1-Bromo-4-fluoro-2-methoxybenzene
- Synonyms
- 1-Bromo-4-fluoro-2-methoxybenzene
Organic Synthesis Intermediate
2-Bromo-5-fluoroanisole serves as a key intermediate in the synthesis of various organic compounds. Its reactive bromine atom allows for diverse coupling reactions, while the fluorine atom and methoxy group influence the electronic properties of the molecule, directing further transformations.
Pharmaceutical Research
This compound can be employed in the discovery and development of new pharmaceutical agents. The presence of fluorine is often desired in drug molecules to modulate metabolic stability and binding affinity.
Materials Science
As a fluorinated aromatic compound, 2-Bromo-5-fluoroanisole may find applications in the development of novel materials with specific electronic or physical properties, such as in the field of organic electronics.
| Molecular weight | 205.02 |
|---|---|
| Empirical formula | C7H6BrFO |
| Assay | 99% |
| Boiling point | 143-145 °C/760 mmHg |
| Density | 1.5983 g/mL at 25 °C |
| Refractive index | n20/D 1.542 |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5-fluoroanisole used for?
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2-Bromo-5-fluoroanisole is primarily used as a versatile intermediate in organic synthesis, including in pharmaceutical research and materials science.
What is the CAS number and formula for 2-Bromo-5-fluoroanisole?
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The CAS number is 450-88-4 and the empirical formula is C7H6BrFO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-5-fluoroanisole with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 2-Bromo-5-fluoroanisole?
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2-Bromo-5-fluoroanisole is classified as a Warning substance, with hazards H302 (Harmful if swallowed) and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is 2-Bromo-5-fluoroanisole packed, shipped, and exported?
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2-Bromo-5-fluoroanisole is packed according to relevant safety and transport regulations. Tech Serve Solutions is experienced in exporting chemicals globally.
How can I request a sample or a quote for 2-Bromo-5-fluoroanisole?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing your requirements.
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