2-Amino-5-chloro-2′-fluorobenzophenone
2-Amino-5-chloro-2′-fluorobenzophenone (CAS: 784-38-3) is a fluorinated organic building block with the molecular formula C13H9ClFN. This compound is an essential intermediate, particularly recognised for its utility in the synthesis of various benzodiazepine derivatives, including diazepam analogues. Available at a purity of 98%, it serves as a key reagent in specialised chemical synthesis and research applications requiring precise molecular structures.
Synthesis of Benzodiazepines
This compound is a crucial precursor in the synthesis of benzotriazepine derivatives and related benzodiazepines, notably those structurally similar to diazepam. Its specific chemical structure facilitates the formation of these important pharmacological scaffolds.
Fluorinated Building Block
As an aryl fluorinated building block, it provides a versatile starting point for introducing both amino, chloro, and fluoro-phenyl ketone functionalities into larger organic molecules. This makes it valuable in medicinal chemistry research and development.
Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic syntheses, enabling the construction of complex molecular architectures. Its reactivity allows for diverse synthetic transformations in research laboratories and fine chemical production.
| Molecular weight | 249.67 |
|---|---|
| Linear formula | H2NC6H3(Cl)C(O)C6H4F |
| Assay | 98% |
| Application | Employed in the syntheses of benzotriazepines1 and diazepam-related benzodiazepines.2 |
| Melting point | 95-98 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-chloro-2′-fluorobenzophenone primarily used for?
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It is primarily used in the synthesis of benzotriazepine and diazepam-related benzodiazepine derivatives, serving as a key organic building block in chemical synthesis.
What are the CAS number and molecular formula for this compound?
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The CAS number is 784-38-3 and the molecular formula is C13H9ClFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-chloro-2′-fluorobenzophenone with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should 2-Amino-5-chloro-2′-fluorobenzophenone be handled safely?
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This compound is classified as a warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area, avoiding dust formation. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
Is this chemical controlled or scheduled?
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The provided data does not indicate that 2-Amino-5-chloro-2′-fluorobenzophenone (CAS: 784-38-3) is a controlled or scheduled substance.
How can I request a quote or sample?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via the website or direct email, providing the product name and CAS number (784-38-3).
How is this chemical typically packed and exported?
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Tech Serve Solutions exports fine chemicals globally, adhering to international shipping regulations. Specific packaging details are confirmed upon order, ensuring product integrity and safety during transit.
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