2-Amino-5-chloro-3-fluoropyridine
2-Amino-5-chloro-3-fluoropyridine (CAS 246847-98-3) is a pyridine derivative with the molecular formula C5H4ClFN2 and a molecular weight of 146.55 g/mol. This halogenated and fluorinated heterocyclic building block is primarily used in chemical synthesis. Its specific structure makes it valuable for introducing complex functionalities into organic molecules, particularly in the development of novel compounds within pharmaceutical and agrochemical research. TSS supplies this compound with an assay of 97%.

Pharmaceutical Intermediate
Utilised as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique halogen and fluorine substitution pattern enables the creation of molecules with specific biological activities and improved pharmacokinetic properties.
Agrochemical Research
Serves as a precursor in the development of new pesticides, herbicides, and fungicides. The incorporation of fluorine and chlorine atoms can enhance the efficacy and stability of agrochemical compounds.
Organic Synthesis
A versatile reagent in academic and industrial organic synthesis laboratories for constructing complex heterocyclic systems. It is particularly useful for researchers exploring structure-activity relationships in medicinal chemistry.
Material Science
Potential application in the synthesis of advanced materials and specialty polymers where fluorinated pyridine moieties can impart desirable electronic or physical properties.
| Molecular weight | 146.55 |
|---|---|
| Empirical formula | C5H4ClFN2 |
| Assay | 97% |
| Melting point | 91-95 °C |


Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-50 |
| Safety statements (S) | 36/37-38-45-61-63 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-chloro-3-fluoropyridine used for?
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2-Amino-5-chloro-3-fluoropyridine (CAS 246847-98-3) is primarily used as a building block in chemical synthesis, particularly for pharmaceuticals and agrochemicals. Its specific structure with halogen and fluorine substituents makes it valuable for introducing these features into more complex molecules.
What are the CAS number and formula for 2-Amino-5-chloro-3-fluoropyridine?
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The CAS number for 2-Amino-5-chloro-3-fluoropyridine is 246847-98-3. Its empirical formula is C5H4ClFN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-chloro-3-fluoropyridine with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Amino-5-chloro-3-fluoropyridine be handled safely?
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2-Amino-5-chloro-3-fluoropyridine is classified as toxic and an environmental hazard (GHS06, GHS09). It is harmful if swallowed, in contact with skin, and if inhaled. It also causes serious eye irritation and is very toxic to aquatic life. Handle with appropriate personal protective equipment (gloves, eye protection, respiratory protection) in a well-ventilated area, and avoid release into the environment.
How is 2-Amino-5-chloro-3-fluoropyridine packed and exported?
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2-Amino-5-chloro-3-fluoropyridine is packed according to industry standards for hazardous chemicals and exported globally by TSS, adhering to all relevant shipping regulations for toxic substances (UN 2811, 6.1/PGIII).
How can I request a sample or quote for 2-Amino-5-chloro-3-fluoropyridine?
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To request a sample or a quote for 2-Amino-5-chloro-3-fluoropyridine, please contact the TSS sales team via our website or by phone, providing your specific requirements and shipping details.
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