2,5-Dimethoxybenzyl alcohol
2,5-Dimethoxybenzyl alcohol (CAS 33524-31-1), with the molecular formula (CH3O)2C6H3CH2OH and a molecular weight of 168.19 g/mol, is a versatile organic building block. This aromatic alcohol serves as a key intermediate in various chemical syntheses. Its applications include the preparation of complex organic molecules such as substituted benzaldehydes and anthracyclines, as well as in the synthesis of pillar[n]arenes through cyclooligomerization reactions. It is offered by Tech Serve Solutions with a minimum purity of 99%.
- Synonyms
- (CH3O)2C6H3CH2OH

Synthesis of Aromatic Aldehydes
2,5-Dimethoxybenzyl alcohol is utilized as a starting material in the synthesis of complex aromatic aldehydes, such as [(S)S]-3,6-dimethoxy-2-(p-tolylsulfinyl)-benzaldehyde, contributing to the development of novel organic compounds.
Intermediate in Pharmaceutical Synthesis
This compound has been employed in synthetic routes towards pharmaceutical agents, including its use in the synthesis of daunorubicinone, a key component in certain anti-cancer drugs.
Preparation of Pillar[n]arenes
The chemical serves as a precursor for the cyclooligomerization reaction leading to the formation of pillar[n]arenes (n=5 or 6) when reacted with appropriate Lewis acid catalysts, facilitating the synthesis of macrocyclic compounds.
| Molecular weight | 168.19 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2OH |
| Assay | 99% |
| Boiling point | 122-125 °C/1 mmHg(lit.) |
| Density | 1.173 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.547(lit.) |
| Application | 2,5-Dimethoxybenzyl alcohol was used as starting reagent in the synthesis of [(S)S]-3,6-dimethoxy-2-(p-tolylsulfinyl)-benzaldehyde1. It was used in the synthesis of daunornycinone2. It was also used in the preparation of pillar[n]arenes (n = 5 or 6) via cyclooligomerization reaction with an appropriate Lewis acid catalyst3. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dimethoxybenzyl alcohol used for?
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2,5-Dimethoxybenzyl alcohol is primarily used as a starting reagent in organic synthesis, including the preparation of specific aromatic aldehydes, pharmaceutical intermediates like daunorubicinone, and pillar[n]arenes.
What are the CAS number and chemical formula for 2,5-Dimethoxybenzyl alcohol?
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The CAS number for 2,5-Dimethoxybenzyl alcohol is 33524-31-1, and its linear chemical formula is (CH3O)2C6H3CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dimethoxybenzyl alcohol with a minimum assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 2,5-Dimethoxybenzyl alcohol be handled safely?
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When handling 2,5-Dimethoxybenzyl alcohol, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. Use a half-mask respirator or a multi-purpose combination respirator cartridge as indicated by safety assessments. Ensure adequate ventilation.
How is 2,5-Dimethoxybenzyl alcohol packed and shipped?
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2,5-Dimethoxybenzyl alcohol is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions. Specific packaging details can be provided upon request.
How can I request a quote or sample for 2,5-Dimethoxybenzyl alcohol?
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To request a quote or a sample of 2,5-Dimethoxybenzyl alcohol, please contact our sales department through the website or by phone, providing your specific requirements.
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