2,5-Dimethoxybenzylzinc chloride solution
2,5-Dimethoxybenzylzinc chloride solution (CAS: 352530-32-6) is an organozinc halide reagent with a molecular weight of 252.03. Supplied as a 0.5 M solution in THF, it is a key intermediate in organic synthesis. This reagent is primarily utilised in carbon-carbon bond formation reactions and for the introduction of the 2,5-dimethoxybenzyl group into organic molecules. Its reactivity profile makes it valuable in complex molecule construction within pharmaceutical and fine chemical research.
- Synonyms
- (CH3O)2C6H3CH2ZnCl
Organozinc Reagent in Organic Synthesis
Utilised for carbon-carbon bond formation through cross-coupling reactions. It serves as a nucleophilic source of the 2,5-dimethoxybenzyl group.
Introduction of 2,5-Dimethoxybenzyl Moiety
Facilitates the precise incorporation of the 2,5-dimethoxybenzyl structural unit into diverse organic frameworks. This is important in the synthesis of biologically active compounds.
Pharmaceutical Intermediate Synthesis
A valuable building block in the multi-step synthesis of complex pharmaceutical intermediates where precise functional group installation is critical.
Fine Chemical Manufacturing
Employed in the production of specialty and fine chemicals, leveraging its specific reactivity for targeted molecular assembly.
| Molecular weight | 252.03 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2ZnCl |
| Boiling point | 65 °C |
| Density | 0.998 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dimethoxybenzylzinc chloride solution used for?
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2,5-Dimethoxybenzylzinc chloride solution is primarily used as an organozinc reagent in organic synthesis for carbon-carbon bond formation and for introducing the 2,5-dimethoxybenzyl group into organic molecules, particularly in the synthesis of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for 2,5-Dimethoxybenzylzinc chloride solution?
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The CAS number is 352530-32-6 and the linear formula is (CH3O)2C6H3CH2ZnCl.
What grade and purity does Tech Serve Solutions supply for 2,5-Dimethoxybenzylzinc chloride solution?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not represent it as USP, BP, EP or pharmacopoeia grade. Please refer to the Certificate of Analysis for specific purity and assay details.
How should 2,5-Dimethoxybenzylzinc chloride solution be handled and stored?
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This compound is flammable and reacts violently with water; it can also cause skin, eye, and respiratory irritation, and is suspected of causing cancer. Store refrigerated at 2-8°C under an inert atmosphere. Handle with extreme caution, avoiding contact with water, air, and ignition sources. Appropriate personal protective equipment is mandatory.
Is 2,5-Dimethoxybenzylzinc chloride solution shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents. We export this product worldwide, adhering to all relevant shipping regulations for hazardous materials.
How can I request a quote or sample for 2,5-Dimethoxybenzylzinc chloride solution?
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To request a quote or sample, please visit the product page on our website and use the 'Request Quote' or 'Request Sample' buttons, or contact our sales team directly via email or phone.
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