2,5-Dimethoxybenzoic acid
2,5-Dimethoxybenzoic acid (CAS: 2785-98-0) is an organic compound with the linear formula (CH3O)2C6H3CO2H and a molecular weight of 182.17 g/mol. As a valuable building block, it plays a role in organic synthesis, particularly in the preparation of complex molecules. Its utility is demonstrated in the synthesis of natural products like galbulimima alkaloid GB 13 and in the creation of 3,4-dihydrofluoren-2(1H)-ones.
- Synonyms
- (CH3O)2C6H3CO2H

Synthesis of Galbulimima Alkaloid GB 13
2,5-Dimethoxybenzoic acid serves as a key intermediate in the multi-step synthesis of the complex natural product galbulimima alkaloid GB 13. Its specific structure allows for its incorporation into the intricate carbon framework of the target alkaloid.
Preparation of Dihydrofluorenones
This compound is utilised in the synthesis of 3,4-dihydrofluoren-2(1H)-ones via reductive alkylation reactions. This application highlights its utility in forming cyclic ketone structures important in various chemical research areas.
Organic Building Block
As a versatile organic building block, 2,5-Dimethoxybenzoic acid is employed in diverse chemical syntheses. Its functional groups enable participation in a range of reactions for creating novel organic molecules.
| Molecular weight | 182.17 |
|---|---|
| Linear formula | (CH3O)2C6H3CO2H |
| Assay | 98% |
| Application | 2,5-Dimethoxybenzoic acid has been used in synthesis of:• galbulimima alkaloid GB 131• 3,4-dihydrofluoren-2(1H)-ones via reductive alkylation2 |
| Melting point | 76-78 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dimethoxybenzoic acid used for?
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2,5-Dimethoxybenzoic acid is primarily used as a building block in organic synthesis. It has been specifically employed in the synthesis of galbulimima alkaloid GB 13 and 3,4-dihydrofluoren-2(1H)-ones.
What is the CAS number and formula for 2,5-Dimethoxybenzoic acid?
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The CAS number for 2,5-Dimethoxybenzoic acid is 2785-98-0. Its linear formula is (CH3O)2C6H3CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dimethoxybenzoic acid with a minimum purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2,5-Dimethoxybenzoic acid be handled safely?
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2,5-Dimethoxybenzoic acid is an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. If in eyes, rinse cautiously with water for several minutes. If inhaled, move to fresh air. In case of contact, wash skin thoroughly.
Is 2,5-Dimethoxybenzoic acid a controlled substance?
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The provided data does not indicate that 2,5-Dimethoxybenzoic acid is a controlled substance. However, users should always verify local regulations.
How is 2,5-Dimethoxybenzoic acid packed and shipped?
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Tech Serve Solutions packs and exports chemicals in compliance with international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or quote for 2,5-Dimethoxybenzoic acid?
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To request a sample or a quotation for 2,5-Dimethoxybenzoic acid, please contact our sales department through the website or via direct email, providing your contact details and the quantity required.
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