2,5-Dimethoxybenzenesulfonyl chloride
2,5-Dimethoxybenzenesulfonyl chloride (CAS: 1483-28-9) is an organic compound with the molecular formula (CH3O)2C6H3SO2Cl and a molecular weight of 236.67 g/mol. This sulfonyl halide serves as a valuable intermediate and building block in organic synthesis. It is employed in the construction of more complex molecules, particularly where a 2,5-dimethoxybenzenesulfonyl moiety is required. Its reactivity makes it useful in various chemical transformations.
- Synonyms
- (CH3O)2C6H3SO2Cl

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of diverse organic compounds. It facilitates the introduction of the 2,5-dimethoxybenzenesulfonyl group into target molecules.
Pharmaceutical Research
Can be employed in the development of novel pharmaceutical agents. Its structure allows for modifications to create potential drug candidates.
Material Science
May be used in the creation of specialised polymers or functional materials. The sulfonyl group offers potential for unique chemical properties.
| Molecular weight | 236.67 |
|---|---|
| Linear formula | (CH3O)2C6H3SO2Cl |
| Assay | 98% |
| Melting point | 112-116 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dimethoxybenzenesulfonyl chloride used for?
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2,5-Dimethoxybenzenesulfonyl chloride (CAS: 1483-28-9) is primarily used as an intermediate and building block in organic synthesis, particularly for introducing the 2,5-dimethoxybenzenesulfonyl moiety into target molecules.
What are the CAS number and formula for 2,5-Dimethoxybenzenesulfonyl chloride?
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The CAS number is 1483-28-9, and the linear formula is (CH3O)2C6H3SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dimethoxybenzenesulfonyl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2,5-Dimethoxybenzenesulfonyl chloride be handled?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, is essential. Handle in a well-ventilated area and follow strict safety protocols.
Is 2,5-Dimethoxybenzenesulfonyl chloride a controlled substance?
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The provided data does not indicate that 2,5-Dimethoxybenzenesulfonyl chloride is a controlled substance.
How is 2,5-Dimethoxybenzenesulfonyl chloride packed and exported?
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2,5-Dimethoxybenzenesulfonyl chloride is packed according to industry standards for hazardous materials and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample of 2,5-Dimethoxybenzenesulfonyl chloride?
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To request a quote or sample, please use the contact form on our website or reach out to our sales team with your specific requirements.
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