Methylphosphonic dichloride
Methylphosphonic dichloride (CAS: 676-97-1, CH3P(O)Cl2) is a reactive organophosphorus compound with a molecular weight of 132.91 g/mol. It is characterised by its role as a versatile intermediate in chemical synthesis. Notably, it participates in condensation reactions with various organic compounds, making it a valuable precursor in the production of specialised chemicals.
- IUPAC
- Dichloromethylphosphine oxide,Methanephosphonyl chloride,Methylphosphonodichloridic acid,Methylphosphonyl chloride,Methylphosphonyl dichloride
- Synonyms
- Dichloromethylphosphine oxideMethanephosphonyl chlorideMethylphosphonodichloridic acidMethylphosphonyl chlorideMethylphosphonyl dichloride

Chemical Synthesis Intermediate
Methylphosphonic dichloride serves as a key building block in organic synthesis. It readily undergoes condensation reactions, particularly with aminobenzenes and alcohols, to form new organophosphorus compounds. This reactivity makes it essential for creating complex molecules in research and industrial settings.
Phosphorus Precursor
As a phosphorus-containing compound, it acts as a precursor in reactions where the introduction of a methylphosphonyl group is required. Its utility extends to the development of novel materials and functionalised compounds.
Reagent in Organic Reactions
The dichloride functionality allows for nucleophilic substitution reactions, enabling its use as a reagent for modifying other molecules. Its applications span various fields requiring tailored phosphorus chemistry.
| Molecular weight | 132.91 |
|---|---|
| Linear formula | CH3P(O)Cl2 |
| Assay | 98% |
| Boiling point | 163 °C(lit.) |
| Density | 1.468 g/mL at 25 °C(lit.) |
| Vapour pressure | 760 mmHg (163 °C) |
| Application | Undergoes condensation reactions with aminobenzenes1,2 and alcohols.3 |
| Melting point | 35-37 °C |


Hazard statements
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3390 6.1/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 14-26-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Contact with water liberates toxic gas., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methylphosphonic dichloride used for?
+
Methylphosphonic dichloride is primarily used as an intermediate in chemical synthesis, particularly for condensation reactions with aminobenzenes and alcohols, and as a phosphorus precursor.
What is the CAS number and formula for Methylphosphonic dichloride?
+
The CAS number is 676-97-1 and the chemical formula is CH3P(O)Cl2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Methylphosphonic dichloride with an assay of 98%. It is supplied as a technical or research grade; TSS does not represent it as USP, BP, or EP grade.
How should Methylphosphonic dichloride be handled safely?
+
Methylphosphonic dichloride is a corrosive substance that reacts violently with water, liberating toxic gas. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including eyeshields, faceshields, gloves, and a P2 respirator cartridge. Refer to the safety data sheet for full handling instructions.
Is Methylphosphonic dichloride a controlled substance?
+
The provided data does not indicate that Methylphosphonic dichloride is a controlled substance. However, users should always comply with local and international regulations regarding its purchase and use.
How is Methylphosphonic dichloride packed, shipped, and exported?
+
As a specialist global supplier, Tech Serve Solutions ensures that Methylphosphonic dichloride is packed, shipped, and exported in compliance with all relevant international transportation and safety regulations for hazardous materials.
How can I request a sample or quote for Methylphosphonic dichloride?
+
To request a sample or a quote for Methylphosphonic dichloride, please contact the TSS sales team through the website or by phone, providing your specific requirements and contact details.
▶ Related products

Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis