2,4-Dichlorophenylzinc iodide solution
2,4-Dichlorophenylzinc iodide (CAS 352530-42-8), with the linear formula Cl2C6H3ZnI and a molecular weight of 338.29 g/mol, is an organozinc halide. This compound is supplied as a 0.5 M solution in THF. It serves as a valuable reagent in organic synthesis, particularly for introducing the 2,4-dichlorophenyl group in various chemical transformations. Its reactive nature necessitates careful handling and storage under refrigeration.
- Synonyms
- Cl2C6H3ZnI
Organozinc Reagent in Cross-Coupling Reactions
2,4-Dichlorophenylzinc iodide is employed in organometallic cross-coupling reactions, such as Negishi coupling, enabling the formation of carbon-carbon bonds with high selectivity. It facilitates the introduction of the 2,4-dichlorophenyl moiety onto diverse organic scaffolds.
Synthesis of Pharmaceutical Intermediates
This organozinc compound can be utilised in the multi-step synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its reactivity profile allows for controlled functionalization in the development of new drug candidates.
Chemical Research and Development
As a specialized organozinc halide, 2,4-Dichlorophenylzinc iodide is a useful tool in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities. It aids in the study of organometallic chemistry.
| Molecular weight | 338.29 |
|---|---|
| Linear formula | Cl2C6H3ZnI |
| Boiling point | 65 °C |
| Density | 1.048 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichlorophenylzinc iodide used for?
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2,4-Dichlorophenylzinc iodide is primarily used as a reagent in organic synthesis, particularly in cross-coupling reactions like Negishi coupling, for introducing the 2,4-dichlorophenyl group. It is also utilized in chemical research and development and the synthesis of pharmaceutical intermediates.
What is the CAS number and formula for 2,4-Dichlorophenylzinc iodide?
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The CAS number for 2,4-Dichlorophenylzinc iodide is 352530-42-8, and its linear formula is Cl2C6H3ZnI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dichlorophenylzinc iodide as a 0.5 M solution in THF. The specific assay and purity details are available upon request and for specific batches. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,4-Dichlorophenylzinc iodide be handled and stored?
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2,4-Dichlorophenylzinc iodide is flammable and can cause serious eye irritation, respiratory irritation, and may cause cancer. It may also form explosive peroxides. It should be stored at 2-8°C and handled with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet for detailed handling instructions.
How is 2,4-Dichlorophenylzinc iodide packed, shipped, and exported?
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2,4-Dichlorophenylzinc iodide is packed according to UN 2056 regulations for flammable liquids. It is shipped and exported globally by Tech Serve Solutions, adhering to all relevant international shipping and hazardous materials transportation guidelines.
How can I request a sample or a quote for 2,4-Dichlorophenylzinc iodide?
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To request a sample or a quote for 2,4-Dichlorophenylzinc iodide, please contact the Tech Serve Solutions sales team via our website or by phone. Please specify the quantity and any other relevant details for your inquiry.
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