2,4-Dichloropyridine-3-boronic acid pinacol ester
2,4-Dichloropyridine-3-boronic acid pinacol ester (CAS 1257651-49-2) is a chemical compound with the molecular formula C11H14BCl2NO2. It is a derivative of pyridine and a member of the boronate ester class, featuring a pinacol ester group attached to a dichlorinated pyridine ring. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions.
- IUPAC
- 2,4-Dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Synonyms
- 2,4-Dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Suzuki-Miyaura Coupling Reactions
This boronate ester is a key reagent for Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of carbon-carbon bonds by reacting with aryl or vinyl halides and triflates under palladium catalysis.
Heteroaryl Synthesis
It is employed in the synthesis of complex heteroaromatic compounds, enabling the introduction of a 2,4-dichloropyridin-3-yl moiety into various molecular structures.
Pharmaceutical Intermediate
The compound finds application as an intermediate in the development of novel pharmaceutical agents, where the pyridine core and its substituents are integral to biological activity.
Materials Science
Used in the creation of functional materials, potentially for applications in organic electronics or as ligands in coordination chemistry due to the pyridine nitrogen atom.
| Molecular weight | 273.95 |
|---|---|
| Empirical formula | C11H14BCl2NO2 |
| Assay | 97% |
| Melting point | 63-67 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichloropyridine-3-boronic acid pinacol ester used for?
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2,4-Dichloropyridine-3-boronic acid pinacol ester is primarily used as a building block in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions for forming carbon-carbon bonds, and in the synthesis of complex heteroaromatic compounds and pharmaceutical intermediates.
What is the CAS number and molecular formula?
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The CAS number is 1257651-49-2, and the molecular formula is C11H14BCl2NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with this chemical?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment.
How is this chemical packaged and shipped?
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This chemical is carefully packaged and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or a quote for 2,4-Dichloropyridine-3-boronic acid pinacol ester, please contact our sales team through the website or by phone.
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