2,4-Dichloropyridine-3-carbonyl chloride
2,4-Dichloropyridine-3-carbonyl chloride (CAS: 607351-40-6) is a pyridinic organic compound with the molecular formula C6H2Cl3NO and a molecular weight of 210.45 g/mol. This acid halide serves as a valuable intermediate and building block in organic synthesis, particularly for the construction of complex heterocyclic molecules. Its reactive carbonyl chloride group facilitates nucleophilic acyl substitution reactions, making it a useful reagent for introducing the 2,4-dichloronicotinoyl moiety into various chemical structures.
- IUPAC
- 2,4-Dichloronicotinoyl chloride
- Synonyms
- 2,4-Dichloronicotinoyl chloride
Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic synthesis for the preparation of pharmaceuticals, agrochemicals, and specialty materials. Its structure allows for further functionalisation and incorporation into larger molecular frameworks.
Heterocyclic Chemistry Building Block
Serves as a versatile building block for the synthesis of substituted pyridines and other heterocyclic compounds. The presence of chlorine atoms offers potential sites for further chemical modification or displacement reactions.
Reagent for Acylation
The reactive carbonyl chloride moiety readily participates in acylation reactions with nucleophiles such as alcohols, amines, and thiols, enabling the formation of esters, amides, and thioesters.
| Molecular weight | 210.45 |
|---|---|
| Empirical formula | C6H2Cl3NO |
| Assay | 97% |
| Density | 1.518 g/mL at 25 °C |
| Refractive index | n20/D 1.562 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichloropyridine-3-carbonyl chloride used for?
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2,4-Dichloropyridine-3-carbonyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly in the creation of pharmaceuticals, agrochemicals, and complex heterocyclic molecules.
What is the CAS number and molecular formula for this compound?
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The CAS number is 607351-40-6, and the molecular formula is C6H2Cl3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum purity of 97%. It is suitable for research and general chemical synthesis. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for 2,4-Dichloropyridine-3-carbonyl chloride?
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This compound is classified as corrosive (Danger, H314) and can cause severe skin burns and eye damage. It is essential to handle it with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling and emergency procedures.
How is 2,4-Dichloropyridine-3-carbonyl chloride packed and shipped?
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This chemical is shipped in compliance with UN 3265 regulations for corrosive liquids, acidic, organic, n.o.s. Packaging is designed to maintain product integrity and ensure safe transport.
How can I request a quote or sample?
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Please contact our sales department via the website or by telephone to request a quotation or a sample of 2,4-Dichloropyridine-3-carbonyl chloride.
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