2,4,6-Trimethylbenzenesulfonohydrazide
2,4,6-Trimethylbenzenesulfonohydrazide (CAS 16182-15-3) is a chemical compound with the molecular formula (CH₃)₃C₆H₂SO₂NHNH₂ and a molecular weight of 214.28 g/mol. It functions as a key building block in organic synthesis. Notably, it has been utilised in the preparation of specific complex organic molecules, including certain alkaloid structures and novel sulfonohydrazide derivatives. This compound is supplied by Tech Serve Solutions with a minimum assay of 97%.
- IUPAC
- 2-Mesitylenesulfonohydrazide
- Synonyms
- 16182-15-3(CH3)3C6H2SO2NHNH22-Mesitylenesulfonohydrazide

Organic Synthesis Intermediate
2,4,6-Trimethylbenzenesulfonohydrazide serves as a valuable intermediate in the synthesis of complex organic molecules. It has been employed in the construction of novel chemical entities, contributing to advancements in synthetic chemistry research.
Alkaloid Synthesis
This compound has found application in the synthetic pathways leading to the formation of complanadine alkaloids. Its specific structural features allow for its incorporation into intricate natural product synthesis.
Derivative Synthesis
It has been used in the synthesis of specific sulfonohydrazide derivatives, such as (E)-N′-(1-((1S*,4aR*,8aR*)-1-hydroxydecahydronaphthalen-4a-yl)ethylidene)-2,4,6-trimethylbenzenesulfonohydrazide. This highlights its utility in creating tailored molecular structures.
| Molecular weight | 214.28 |
|---|---|
| Linear formula | (CH3)3C6H2SO2NHNH2 |
| Assay | 97% |
| Application | 2,4,6-Trimethylbenzenesulfonohydrazide has been used in the synthesis of:• (E)-N′-(1-((1S*,4aR*,8aR*)-1-hydroxydecahydronaphthalen-4a-yl)ethylidene)-2,4,6-trimethylbenzenesulfonohydrazide1• complanadine alkaloids2 |
| Melting point | 112-114 °C (dec.)(lit.) |


Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 5-11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,6-Trimethylbenzenesulfonohydrazide used for?
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2,4,6-Trimethylbenzenesulfonohydrazide is primarily used as a building block in organic synthesis and has been employed in the preparation of specific organic molecules, including certain alkaloid structures and novel sulfonohydrazide derivatives.
What are the CAS number and formula for 2,4,6-Trimethylbenzenesulfonohydrazide?
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The CAS number for 2,4,6-Trimethylbenzenesulfonohydrazide is 16182-15-3, and its linear formula is (CH₃)₃C₆H₂SO₂NHNH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4,6-Trimethylbenzenesulfonohydrazide with a minimum assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety concerns when handling this chemical?
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2,4,6-Trimethylbenzenesulfonohydrazide is classified as a flammable solid (H228) and an irritant to skin (H315), eyes (H319), and the respiratory system (H335). It requires careful handling with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, and should be kept away from heat and ignition sources.
How is 2,4,6-Trimethylbenzenesulfonohydrazide packed and exported?
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This product is packed according to relevant shipping regulations for flammable solids (UN 1325, 4.1/PGII) and is exported globally by Tech Serve Solutions, adhering to all international transport requirements.
How can I request a sample or quote for 2,4,6-Trimethylbenzenesulfonohydrazide?
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To request a sample or a quotation for 2,4,6-Trimethylbenzenesulfonohydrazide, please contact the Tech Serve Solutions sales team via the website or by phone, providing your contact details and the quantity required.
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