2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid
2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid (CAS: 1447-14-9) is a specialised organic building block with the molecular formula Cl2C3H2(CH3)CO2H and a molecular weight of 169.01 g/mol. This compound is primarily utilised in organic synthesis, particularly in the preparation of pharmaceutical intermediates. Its dichlorocyclopropane structure offers unique reactivity for constructing complex molecules, including its documented use in solid-phase synthesis for producing inhibitors of amyloid-beta production.
- Synonyms
- Cl2C3H2(CH3)CO2H
Organic Synthesis Building Block
This compound serves as a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. Its reactive dichlorocyclopropane moiety is valuable for introducing specific functionalities.
Pharmaceutical Intermediate Preparation
It is employed in the synthesis of various pharmaceutical intermediates. The unique structural features contribute to the development of novel therapeutic agents.
Research and Development
Utilised in academic and industrial research laboratories for exploring new synthetic routes and developing novel compounds. Its specific application in solid-phase synthesis for amyloid-beta production inhibitors highlights its utility.
| Molecular weight | 169.01 |
|---|---|
| Linear formula | Cl2C3H2(CH3)CO2H |
| Assay | 98% |
| Boiling point | 85 °C/8 mmHg(lit.) |
| Application | 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid was used in solid phase synthesis of α-hydroxy esters, inhibitors of amyloid-β production1. |
| Melting point | 60-65 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid used for?
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2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid is used as a building block in organic synthesis, particularly for preparing pharmaceutical intermediates. It has been documented for use in solid-phase synthesis of alpha-hydroxy esters and inhibitors of amyloid-beta production.
What is the CAS number and chemical formula for 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid?
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The CAS number is 1447-14-9 and the chemical formula is Cl2C3H2(CH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid with an assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Is 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid.
How can I request a quote or sample for 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid?
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Please contact our sales team via the website or directly by phone to request a quote or sample for 2,2-Dichloro-1-methyl-cyclopropanecarboxylic acid.
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