2,2,2-Tribromoethyl dichlorophosphate
2,2,2-Tribromoethyl dichlorophosphate (CAS 53676-22-5) is a phosphorus halide compound with the linear formula CBr3CH2OP(O)Cl2 and a molecular weight of 399.63 g/mol. This chemical serves as a key reagent in sophisticated organic synthesis, particularly in the preparation of oligonucleotides and oligodeoxynucleotides. Supplied by Tech Serve Solutions with a minimum assay of 97%, it is essential for research and development in the pharmaceutical and biotechnology sectors.
- IUPAC
- 2,2,2-Tribromoethyl phosphorodichloridate
- Synonyms
- 53676-22-5CBr3CH2OP(O)Cl22,2,2-Tribromoethyl phosphorodichloridate
Oligonucleotide Synthesis
Serves as a critical reagent for the synthesis of oligonucleotides and oligodeoxynucleotides. Its structure facilitates the phosphitylation process required for building DNA and RNA chains.
Organic Building Block
A valuable building block in organic synthesis, offering a reactive dichlorophosphate moiety coupled with a tribromoethyl group. This allows for diverse chemical transformations and the construction of complex molecules.
Phosphorus Chemistry Research
Utilised in academic and industrial research settings focused on phosphorus chemistry and the development of novel phosphorus-containing compounds. Its unique halogenation pattern offers specific reactivity.
| Molecular weight | 399.63 |
|---|---|
| Linear formula | CBr3CH2OP(O)Cl2 |
| Assay | 97% |
| Boiling point | 90-92 °C/0.4 mmHg(lit.) |
| Application | Reagent for oligonucleotide and oligodeoxynucleotide synthesis. |
| Melting point | 34-36 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 22-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Tribromoethyl dichlorophosphate used for?
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2,2,2-Tribromoethyl dichlorophosphate is primarily used as a reagent in oligonucleotide and oligodeoxynucleotide synthesis. It also serves as a versatile building block in organic synthesis and research within phosphorus chemistry.
What are the CAS number and formula for 2,2,2-Tribromoethyl dichlorophosphate?
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The CAS number is 53676-22-5 and the linear formula is CBr3CH2OP(O)Cl2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Tribromoethyl dichlorophosphate with a minimum assay of 97%. This product is not represented as USP, BP, EP, or pharmaceutical grade.
What are the primary safety concerns when handling this chemical?
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This compound is classified as Danger, with hazards including being harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332) and causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, is essential.
How is 2,2,2-Tribromoethyl dichlorophosphate packed and shipped?
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This chemical is shipped as UN 3261, Hazard Class 8, Packing Group II, adhering to strict international shipping regulations for hazardous materials.
How can I request a sample or quote for 2,2,2-Tribromoethyl dichlorophosphate?
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To request a sample or a quote, please contact the Tech Serve Solutions sales department via our website or direct inquiry, providing your details and the product CAS number 53676-22-5.
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